SCHEMBL20809352

SCHEMBL20809352

Cc1cc(C)cc(-c2ncnc3cc(C(C)C)ccc23)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAMKK1 Q8N5S9 2/20 0.39
CAMKK2 Q96RR4 2/20 0.39
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
NPC1 O15118 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TP53 P04637 2/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
EGFR P00533 1/20 0.37
ADORA2A P29274 1/20 0.37
KIT P10721 2/20 0.36
IRAK4 Q9NWZ3 1/20 0.34
PLK1 P53350 1/20 0.33
MAP4K4 O95819 3/20 0.33
LMNA P02545 2/20 0.33
FYN P06241 2/20 0.32
SRC P12931 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24795347 0.88 RXRA (0.35) CAMKK1CAMKK2KDM4EMEN1NPC1
SCHEMBL20809348 0.85 KIT (0.38) CAMKK1CAMKK2KDM4EMEN1NPC1
SCHEMBL24796188 0.82 ADORA2A (0.42) CAMKK1CAMKK2KDM4EALDH1A1MAPT
SCHEMBL19143215 0.80 LMNA (0.36) CAMKK1CAMKK2EGFRKITIRAK4
SCHEMBL20809353 0.78 CAMKK1 (0.37) CAMKK1CAMKK2KDM4EMEN1ALDH1A1
SCHEMBL21162722 0.78 PPARG (0.43) KDM4ENPC1ALDH1A1ADORA2AMAP4K4
SCHEMBL14442426 0.77 IRAK4 (0.41) KDM4EMEN1NPC1ALDH1A1TP53
SCHEMBL19258252 0.77 LMNA (0.41) MEN1ALDH1A1TP53KMT2AHSD17B10
SCHEMBL29530714 0.76 GSK3A (0.37) KDM4EMEN1NPC1ALDH1A1TP53
SCHEMBL20809105 0.76 AURKA (0.37) PLK1MAP4K4LMNAFYNAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402877-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-22 US disclosed
US-20220013734-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2022-01-13 US disclosed
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 CAMKK1 1632/4885CAMKK2 1382/4885KDM4E 4362/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 CAMKK1 1632/4885CAMKK2 1382/4885KDM4E 4362/4885
US-20220402877-A1 ELECTROLUMINESCENT DEVICE MCOLN2, MCOLN1, LDHB CAMKK1 4034/4885CAMKK2 3615/4885KDM4E 1211/4885
US-20220013734-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, TLL1, TLL2 CAMKK1 3244/4885CAMKK2 3597/4885KDM4E 4179/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 CAMKK1 3553/4885CAMKK2 3452/4885KDM4E 3879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.