Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828420 | 0.87 | DGAT1 (0.47) | DGAT1SLC2A1ROCK2MEN1KMT2A | |
| SCHEMBL20828341 | 0.85 | DGAT1 (0.48) | DGAT1SLC2A1ROCK2MEN1KMT2A | |
| SCHEMBL20828421 | 0.84 | SCD (0.43) | DGAT1SLC2A1ROCK2MEN1KMT2A | |
| SCHEMBL20828417 | 0.82 | ROCK2 (0.46) | DGAT1SLC2A1ROCK2MEN1KMT2A | |
| SCHEMBL20820817 | 0.79 | DGAT1 (0.50) | DGAT1SLC2A1ROCK2 | |
| SCHEMBL20828340 | 0.78 | BRAF (0.46) | DGAT1ROCK2 | |
| SCHEMBL20828481 | 0.75 | FFAR1 (0.45) | DGAT1PTGDR2ROCK2 | |
| SCHEMBL20828342 | 0.75 | DGAT1 (0.58) | DGAT1SLC2A1MEN1KMT2A | |
| SCHEMBL20828403 | 0.75 | DGAT1 (0.41) | DGAT1ROCK2 | |
| SCHEMBL20828451 | 0.73 | BRAF (0.44) | SLC2A1PPARGF10KLKB1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |