SCHEMBL20857933

SCHEMBL20857933

COc1ccc(B2OC(C)(C)C(C)(C)O2)c2[nH]c3ccccc3c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.49
▸ KMT2A Q03164 4/20 0.49
▸ MAPT P10636 4/20 0.49
▸ KDM4E B2RXH2 2/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ THRB P10828 1/20 0.49
▸ CYP2C9 P11712 1/20 0.49
▸ HPGD P15428 1/20 0.49
▸ ALOX15 P16050 1/20 0.49
▸ ALOX12 P18054 1/20 0.49
▸ MAPK1 P28482 1/20 0.49
▸ CASP1 P29466 1/20 0.49
▸ CASP7 P55210 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.49
▸ TDP1 Q9NUW8 1/20 0.49
▸ MITF O75030 1/20 0.43
▸ GABRP O00591 1/20 0.43
▸ GABRD O14764 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24026602 0.82 MEN1 (0.39) MEN1KMT2AMAPTGABRPGABRD
SCHEMBL20857944 0.79 DYRK1A (0.48) MEN1KMT2AMAPTGABRPGABRD
SCHEMBL14689628 0.77 MAPT (0.76) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL29675284 0.76 KIF11 (0.49) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL29961225 0.76 KIF11 (0.49) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL16835585 0.76 KIF11 (0.49) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL24564215 0.76 DYRK1A (0.42) MEN1KMT2AMAPTKDM4EGABRP
SCHEMBL5779840 0.76 IDO1 (0.49) MAPTEGFRCA1CA2CA4
SCHEMBL5188186 0.75 KDM4E (0.56) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL17071924 0.75 KMT2A (0.40) MEN1KMT2AMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 — — US disclosed
US-11569449-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2023-01-31 — — US disclosed
US-20220389027-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2022-12-08 — — US disclosed
US-20220059775-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-02-24 — — US disclosed
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2021-09-23 — — US disclosed
EP-3723149-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND NOVEL COMPOUND Idemitsu Kosan Co., Ltd (JP) 2020-10-14 — — EP disclosed
WO-2020115933-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE USING SAME 出光興産株式会社 2020-06-11 — — WO disclosed
US-10680181-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-09 — — US disclosed
US-10672989-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-02 — — US disclosed
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-11-21 — — US disclosed
US-20190221747-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-07-18 — — US disclosed
US-10249832-B1 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L MEN1 1048/4885KMT2A 3104/4885MAPT 1947/4885
US-10249832-B1 Organic electroluminescence device and novel compound OR10J3, KCNH3, OR51E2 MEN1 918/4885KMT2A 2567/4885MAPT 3585/4885
US-10680181-B2 Organic electroluminescence device and novel compound PIEZO1, TMEM109, OXA1L MEN1 1048/4885KMT2A 3104/4885MAPT 1947/4885
US-10672989-B2 Organic electroluminescence device and novel compound LEF1, OR10J3, LUC7L2 MEN1 1399/4885KMT2A 2186/4885MAPT 2613/4885
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L MEN1 1048/4885KMT2A 3104/4885MAPT 1947/4885
US-20220389027-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CCNA1, CRY2 MEN1 716/4885KMT2A 940/4885MAPT 4143/4885
US-20190221747-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND KCNN4, OR10J3, KCNN2 MEN1 688/4885KMT2A 2435/4885MAPT 2875/4885
US-11569449-B2 Organic electroluminescence device and novel compound PIEZO1, TMEM109, OXA1L MEN1 1048/4885KMT2A 3104/4885MAPT 1947/4885
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME OLA1, AOC1, ODC1 MEN1 936/4885KMT2A 1063/4885MAPT 2539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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