Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20869876 | 0.82 | ACHE (0.52) | ACHEEPHX2 | |
| SCHEMBL20100180 | 0.79 | ALDH1A1 (0.53) | EPHX2ALDH1A1LMNAGAA | |
| SCHEMBL20100181 | 0.79 | ALDH1A1 (0.53) | EPHX2ALDH1A1LMNAGAA | |
| SCHEMBL21842269 | 0.79 | ALDH1A1 (0.53) | EPHX2ALDH1A1LMNAGAA | |
| SCHEMBL12543513 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAGAA | |
| SCHEMBL23735666 | 0.76 | POLB (0.49) | EPHX2ALDH1A1CYP3A4RAB9ALMNA | |
| SCHEMBL19686832 | 0.76 | CASP2 (0.59) | EPHX2 | |
| SCHEMBL26709266 | 0.76 | CASP2 (0.59) | EPHX2 | |
| SCHEMBL19960608 | 0.75 | CASP2 (0.62) | EPHX2 | |
| SCHEMBL26700975 | 0.74 | CNR1 (0.47) | EPHX2ALDH1A1CYP3A4RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | LOXL2, LOXL1, LOXL3 | ACHE 3550/4885EPHX2 393/4885ALDH1A1 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.