SCHEMBL20888939

SCHEMBL20888939

Bc1cc(Cl)cc2cc(N)c(C(C)(C)O)nc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20888988 0.79 — —
SCHEMBL20888989 0.77 — —
SCHEMBL20888986 0.77 — —
SCHEMBL20888983 0.73 — —
Reproxalap SCHEMBL29354850 0.72 TNKS (0.39) PGR
Reproxalap SCHEMBL29536691 0.72 TNKS (0.39) PGR
Reproxalap SCHEMBL12228833 0.72 TNKS (0.39) PGR
SCHEMBL20888945 0.72 — —
SCHEMBL18555848 0.71 NR4A2 (0.43) PGR
SCHEMBL29341932 0.70 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230293527-A1 TREATMENT OF INFLAMMATORY DISORDERS ALDEYRA THERAPEUTICS, INC. 2023-09-21 — — US disclosed
US-20230248727-A1 TREATMENT OF INFLAMMATORY DISORDERS ALDEYRA THERAPEUTICS, INC. 2023-08-10 — — US disclosed
US-20230174491-A1 DEUTERATED COMPOUNDS AND USES THEREOF ALDEYRA THERAPEUTICS, INC. 2023-06-08 — — US disclosed
US-20230149383-A1 QUINOLINE COMPOUNDS FOR TREATING LUNG, LIVER, AND KIDNEY DISEASES, DISORDERS, OR CONDITIONS ALDEYRA THERAPEUTICS, INC. 2023-05-18 — — US disclosed
US-20230131929-A1 QUINOLINE COMPOUNDS FOR TREATING RESPIRATORY DISORDERS AND VIRAL INFECTIONS ALDEYRA THERAPEUTICS, INC. 2023-04-27 — — US disclosed
US-11583529-B2 Treatment of inflammatory disorders ALDEYRA THERAPEUTICS, INC. (US) 2023-02-21 — — US disclosed
US-20220133697-A1 INJECTABLE FORMULATIONS ALDEYRA THERAPEUTICS, INC. 2022-05-05 — — US disclosed
US-20210393527-A1 PHARMACEUTICAL FORMULATIONS AND USES THEREOF ALDEYRA THERAPEUTICS, INC. 2021-12-23 — — US disclosed
US-20210353628-A1 TREATMENT OF INFLAMMATORY DISORDERS ALDEYRA THERAPEUTICS, INC. 2021-11-18 — — US disclosed
US-20210347735-A1 DEUTERATED COMPOUNDS AND USES THEREOF ALDEYRA THERAPEUTICS, INC. 2021-11-11 — — US disclosed
US-11046650-B2 Deuterated compounds and uses thereof ALDEYRA THERAPEUTICS, INC. (US) 2021-06-29 — — US disclosed
US-11040039-B2 Treatment of inflammatory disorders ALDEYRA THERAPEUTICS, INC. (US) 2021-06-22 — — US disclosed
US-20200199075-A1 DEUTERATED COMPOUNDS AND USES THEREOF ALDEYRA THERAPEUTICS, INC. 2020-06-25 — — US disclosed
US-20200038392-A1 TOPICAL COMPOSITIONS AND METHODS OF PREPARATION AND USE ALDEYRA THERAPEUTICS, INC. 2020-02-06 — — US disclosed
US-10550085-B2 Deuterated compounds and uses thereof ALDEYRA THERAPEUTICS, INC. (US) 2020-02-04 — — US disclosed
US-20190105322-A1 Treatment of inflammatory disorders ALDEYRA THERAPEUTICS, INC. 2019-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131929-A1 QUINOLINE COMPOUNDS FOR TREATING RESPIRATORY DISORDERS AND VIRAL INFECTIONS MAVS, ACE2, SARS1 PGR 4839/4885
US-11040039-B2 Treatment of inflammatory disorders TNF, NFKBIA, LTB4R2 PGR 1434/4885
US-20230293527-A1 TREATMENT OF INFLAMMATORY DISORDERS TNF, NFKBIA, LTB4R2 PGR 1434/4885
US-11583529-B2 Treatment of inflammatory disorders TNF, NFKBIA, LTB4R2 PGR 1434/4885
US-20210347735-A1 DEUTERATED COMPOUNDS AND USES THEREOF ALDH1A2, SSB, DBH PGR 4684/4885
US-20220133697-A1 INJECTABLE FORMULATIONS ALDH2, CLN6, ALDH1A1 PGR 1924/4885
US-10550085-B2 Deuterated compounds and uses thereof ALDH1A2, SSB, DBH PGR 4684/4885
US-20210353628-A1 TREATMENT OF INFLAMMATORY DISORDERS TNF, NFKBIA, LTB4R2 PGR 1434/4885
US-20230248727-A1 TREATMENT OF INFLAMMATORY DISORDERS TNF, NFKBIA, LTB4R2 PGR 1434/4885
US-20230149383-A1 QUINOLINE COMPOUNDS FOR TREATING LUNG, LIVER, AND KIDNEY DISEASES, DISORDERS, OR CONDITIONS GLS, PYGL, REN PGR 4694/4885
US-20200199075-A1 DEUTERATED COMPOUNDS AND USES THEREOF ALDH1A2, SSB, DBH PGR 4684/4885
US-20210393527-A1 PHARMACEUTICAL FORMULATIONS AND USES THEREOF IL5, CFTR, NQO2 PGR 4711/4885
US-20230174491-A1 DEUTERATED COMPOUNDS AND USES THEREOF ALDH1A2, SSB, DBH PGR 4684/4885
US-20190105322-A1 Treatment of inflammatory disorders TNF, NFKBIA, LTB4R2 PGR 1434/4885
US-11046650-B2 Deuterated compounds and uses thereof ALDH1A2, SSB, DBH PGR 4684/4885
US-20200038392-A1 TOPICAL COMPOSITIONS AND METHODS OF PREPARATION AND USE CUTA, TSLP, ASAH2 PGR 1388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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