Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572629 | 0.85 | ALOX5 (0.45) | — | |
| SCHEMBL7839632 | 0.82 | PPARA (0.51) | — | |
| SCHEMBL9285026 | 0.81 | KDM4E (0.44) | SOD1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL7603000 | 0.80 | PPARA (0.59) | — | |
| SCHEMBL3194516 | 0.79 | PTGS2 (0.35) | SOD1CYP1A2CYP2A6 | |
| SCHEMBL8151669 | 0.79 | KMT2A (0.41) | TSHRTDP1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9571992 | 0.78 | SOD1 (0.55) | SOD1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL9488681 | 0.77 | ALDH1A1 (0.50) | SOD1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL30358275 | 0.77 | ALDH1A1 (0.50) | SOD1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL3817643 | 0.77 | SOD1 (0.46) | SOD1MAPK1L3MBTL1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217850-B | Preparation method of silicon-based ester compound, electrolyte containing silicon-based ester compound and secondary battery | 微宏先进材料公司 | 2023-05-26 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-7282605-B2 | Optically active 2-allylcarboxylic acid derivative and process for producing the same | KANEKA CORPORATION (JP) | 2007-10-16 | — | — | US | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060223152-A1 | Optically active 2-allylcarboxylic acid derivative and process for producing the same | KANEKA CORPORATION (JP) | 2006-10-05 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-5079134-A | X-ray film with improved sharpness, reduced crossover, dye which absorbs in sensitive region of silver halide emulsion | FUJI PHOTO FILM CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0457153-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |
| EP-0456163-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-13 | — | — | EP | disclosed |
| EP-0423742-A2 | Silver halide color reversal photographic photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |
| EP-0423693-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |
| EP-0391405-A2 | Silver halide photographic material and method for processing thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-10 | — | — | EP | disclosed |
| EP-0337490-A2 | Silver halide light-sensitive photographic material | Fuji Photo Film Co., Ltd. (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4859759-A | Siloxane containing benzotriazolyl/tetraalkylpiperidyl substituent | KIMBERLY-CLARK CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0319999-A2 | Silver halide photographic materials | Fuji Photo Film Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |
| US-4259350-A | PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK | SANKYO COMPANY LIMITED (JP) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | SOD1 2911/4885MAPK1 2105/4885L3MBTL1 2575/4885 |
| US-20060223152-A1 | Optically active 2-allylcarboxylic acid derivative and process for producing the same | APEH, NAAA, AADAC | SOD1 4278/4885MAPK1 4700/4885L3MBTL1 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.