Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21048892 | 0.86 | PTGER1 (0.50) | TSHRPOLB | |
| SCHEMBL21048778 | 0.86 | GAA (0.44) | GAAHTTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL21048855 | 0.85 | JAK2 (0.44) | HTTTP53ALDH1A1TSHRNPC1 | |
| SCHEMBL21048821 | 0.82 | ALDH1A1 (0.49) | GAAHTTTP53ALDH1A1TSHR | |
| SCHEMBL21048835 | 0.82 | JAK2 (0.44) | TP53ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL21048978 | 0.79 | TP53 (0.52) | GAATP53ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL21048765 | 0.78 | HTT (0.41) | GAAHTTALDH1A1TSHRPOLB | |
| SCHEMBL21048834 | 0.78 | TP53 (0.42) | GAATP53SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21048953 | 0.76 | LMNA (0.53) | SMN1; SMN2POLB | |
| SCHEMBL20957057 | 0.72 | HSD17B10 (0.46) | GAAHTTTP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143021-B1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER (US) | 2019-06-12 | — | — | EP | disclosed |