SCHEMBL21058382

SCHEMBL21058382

CCCC(=O)N[C@H]1C(O)O[C@H](COC(=O)C(Cc2ccc(OC(=O)OC(C)(C)C)cc2)NC(=O)OC(C)(C)C)[C@@H](O)[C@@H]1O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ITGB3 P05106 2/20 0.38
▸ ITGA2B P08514 2/20 0.38
▸ ACE P12821 1/20 0.38
▸ BACE1 P56817 1/20 0.36
▸ HDAC8 Q9BY41 1/20 0.36
▸ PTPN1 P18031 2/20 0.35
▸ EPHX2 P34913 1/20 0.34
▸ CTSS P25774 6/20 0.34
▸ CTSK P43235 5/20 0.34
▸ KDM1A O60341 1/20 0.34
▸ KLK5 Q9Y337 1/20 0.34
▸ SCN9A Q15858 1/20 0.34
▸ SLC5A1 P13866 1/20 0.33
▸ SLC5A2 P31639 1/20 0.33
▸ CACNA1B Q00975 1/20 0.33
▸ CTSL P07711 1/20 0.33
▸ CTSB P07858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21138668 1.00 ITGB3 (0.38) ITGB3ITGA2BACEBACE1HDAC8
SCHEMBL29777479 0.90 ACE (0.48) ACEEPHX2CTSSCTSKKLK5
SCHEMBL21058353 0.90 ACE (0.48) ACEEPHX2CTSSCTSKKLK5
SCHEMBL21137852 0.85 KDM1A (0.38) ITGB3ITGA2BACEBACE1HDAC8
SCHEMBL25957442 0.83 CTSK (0.36) ACECTSSCTSK
SCHEMBL31353010 0.81 CAPN1 (0.40) CTSSCTSKCTSLCTSB
SCHEMBL21058397 0.77 CTSK (0.35) CTSSCTSKKLK5CTSLCTSB
SCHEMBL21137891 0.77 CTSK (0.35) CTSSCTSKKLK5CTSLCTSB
SCHEMBL21058347 0.73 PTGS2 (0.43) —
SCHEMBL1087185 0.72 ITGB3 (0.65) ITGB3ITGA2BACEHDAC8PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2026-02-17 — — US disclosed
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2025-11-20 — — US disclosed
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2025-05-27 — — US disclosed
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2024-02-15 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA ITGB3 1429/4885ITGA2B 1060/4885ACE 605/4885
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA ITGB3 1927/4885ITGA2B 1511/4885ACE 1293/4885
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, FUT6 ITGB3 1757/4885ITGA2B 1412/4885ACE 925/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA ITGB3 1927/4885ITGA2B 1511/4885ACE 1293/4885
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof SOST, FUT6, SLC5A1 ITGB3 774/4885ITGA2B 1181/4885ACE 1734/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA ITGB3 1429/4885ITGA2B 1060/4885ACE 605/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA ITGB3 1429/4885ITGA2B 1060/4885ACE 605/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA ITGB3 1429/4885ITGA2B 1060/4885ACE 605/4885
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, FUT6 ITGB3 1757/4885ITGA2B 1412/4885ACE 925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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