Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | HINT1 | P49773 | 5/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | KRAS | P01116 | 3/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15841440 | 0.99 | TYMP (0.41) | TYMPHPGDTAS1R3TAS1R1TAAR1 | |
| SCHEMBL2107702 | 0.93 | TYMP (0.44) | TYMPHPGDTAS1R3TAS1R1TAAR1 | |
| SCHEMBL3905624 | 0.89 | HPGD (0.37) | TYMPHPGDTAS1R3TAS1R1TAAR1 | |
| SCHEMBL16401489 | 0.89 | TYMP (0.48) | TYMPHPGDTAS1R3TAS1R1TAAR1 | |
| SCHEMBL2215262 | 0.89 | TYMP (0.43) | TYMPHPGDTAS1R3TAS1R1TAAR1 | |
| SCHEMBL2107681 | 0.89 | HPGD (0.37) | TYMPHPGDTAS1R3TAS1R1TAAR1 | |
| SCHEMBL15878701 | 0.88 | HPGD (0.36) | TYMPHPGDTAS1R3TAS1R1TAAR1 | |
| SCHEMBL2108884 | 0.87 | TYMP (0.53) | TYMPHPGDTAAR1HINT1GSK3A | |
| SCHEMBL16401843 | 0.85 | TYMP (0.48) | TYMPHPGDTAS1R3TAS1R1TAAR1 | |
| SCHEMBL10476437 | 0.84 | TAAR1 (0.40) | TYMPHPGDTAS1R3TAS1R1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995253-B1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | NIPPON SHINYAKU CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-1795536-B1 | PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA | NIPPON SHINYAKU CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8158775-B2 | Method for detaching protecting group on nucleic acid | NIPPON SHINYAKU CO., LTD. (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20090312534-A1 | METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP | NIPPON SHINYAKU CO., LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20090149645-A1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | NIPPON SHINYAKU CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090137790-A1 | METHOD OF CAPPING OLIGONUCLEIC ACID | NIPPON SHINYAKU CO., LTD. (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2017282-A1 | METHOD OF CAPPING OLIGONUCLEIC ACID | Nippon Shinyaku Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-1995252-A1 | METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP | Nippon Shinyaku Co., Ltd. (JP) | 2008-11-26 | — | — | EP | disclosed |
| EP-1995253-A1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | Nippon Shinyaku Co., Ltd. (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-20070282097-A1 | Phosphoramidite Compound And Method For Producing Oligo-Rna | NIPPON SHINYAKU CO., LTD. (JP) | 2007-12-06 | — | — | US | disclosed |
| EP-1795536-A1 | PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA | Nippon Shinyaku Co., Ltd. (JP) | 2007-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312534-A1 | METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP | NSUN2, RNASEH1, RNASE1 | TYMP 321/4885HPGD 2241/4885TAS1R3 3036/4885 |
| US-20090137790-A1 | METHOD OF CAPPING OLIGONUCLEIC ACID | RNGTT, DUT, ADAR | TYMP 122/4885HPGD 3144/4885TAS1R3 4816/4885 |
| US-20070282097-A1 | Phosphoramidite Compound And Method For Producing Oligo-Rna | NSUN2, NSUN3, XRN2 | TYMP 485/4885HPGD 4533/4885TAS1R3 2238/4885 |
| US-20090149645-A1 | METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID | DNASE1, DNASE1L3, NSUN2 | TYMP 149/4885HPGD 2390/4885TAS1R3 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.