Sugi Predict

Sugi Predict / Compounds / SCHEMBL2107437

SCHEMBL2107437

SCHEMBL2107437

CO/C=C(\C(=O)O)n1cccc1C(=O)c1cc(C)cc(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TUBB4A P04350 5/20 0.33
▸ TUBB P07437 5/20 0.33
▸ TUBA3C P0DPH7 5/20 0.33
▸ TUBA1B P68363 5/20 0.33
▸ TUBA4A P68366 5/20 0.33
▸ TUBB4B P68371 5/20 0.33
▸ TUBB3 Q13509 5/20 0.33
▸ TUBB2A Q13885 5/20 0.33
▸ TUBB8 Q3ZCM7 5/20 0.33
▸ TUBA3E Q6PEY2 5/20 0.33
▸ TUBA1A Q71U36 5/20 0.33
▸ TUBA1C Q9BQE3 5/20 0.33
▸ TUBB6 Q9BUF5 5/20 0.33
▸ TUBB2B Q9BVA1 5/20 0.33
▸ TUBB1 Q9H4B7 5/20 0.33
▸ TPMT P51580 1/20 0.33
▸ PPARG P37231 2/20 0.32
▸ PPARA Q07869 2/20 0.32
▸ FNTA P49354 1/20 0.32
▸ FNTB P49356 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2107443 1.00 TUBB4A (0.33) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL22074662 0.90 POLB (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL202895 0.89 KDM4E (0.31) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL2107441 0.87 TPMT (0.37) TPMTPPARGPPARAFNTAFNTB
SCHEMBL9329481 0.87 ALDH1A1 (0.43) MEN1ALDH1A1LMNAMAPTALOX12
SCHEMBL2849656 0.87 TPMT (0.37) TPMTPPARGPPARAFNTAFNTB
SCHEMBL9329486 0.87 ALDH1A1 (0.43) MEN1ALDH1A1LMNAMAPTALOX12
SCHEMBL27338029 0.84 PPARG (0.35) TPMTPPARGPPARAMEN1ALDH1A1
SCHEMBL202897 0.78 TPMT (0.34) TPMTFNTAFNTBMEN1ALDH1A1
SCHEMBL29078328 0.78 LMNA (0.32) ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043600-B2 Microbiocidal compounds SYNGENTA CROP PROTECTION AG (CH) 2024-07-23 — — US disclosed
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-06-18 — — US disclosed
CN-114340374-B Sowing device and method for treating seeds during planting 先正达参股股份有限公司 2024-06-11 — — CN disclosed
US-11882834-B2 Microbiocidal thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 — — US disclosed
EP-4271185-A1 DELIVERY SYSTEM FOR PLANT PROTECTION Omya International AG (CH) 2023-11-08 — — EP disclosed
CN-111303116-B Microbiocidal heterobicyclic derivatives 先正达参股股份有限公司 2023-10-10 — — CN disclosed
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide SYNGENTA PARTICIPATIONS AG (CH) 2023-09-05 — — US disclosed
EP-3717479-B1 MICROBIOCIDAL THIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-07-05 — — EP disclosed
EP-3941898-B1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-07 — — EP disclosed
EP-3244732-B1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS OMYA INT AG (CH) 2023-05-03 — — EP disclosed
US-20030092641-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2003-05-15 — — US disclosed
US-6444667-B1 OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 — — US disclosed
US-5972971-A WOOD PRESERVATIVE CONSISTS OF A MIXTURE OF METACONAZOLE OR AN ACID ADDITION SALT OR METAL COMPLEX AND IMIDACLOPRID OR SALT OR METAL COMPLEX BAYER AKTIENGESELLSCHAFT (DE) 1999-10-26 — — US disclosed
US-5925675-A N-sulfonyliminodithio compounds useful for in plant and material protection BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 — — US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 — — US disclosed
US-5767137-A FOR INDUSTRIAL MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1998-06-16 — — US disclosed
US-5703103-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-30 — — US disclosed
US-5672617-A Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock BAYER AKTIENGESELLSCHAFT (DE) 1997-09-30 — — US disclosed
US-5622546-A Mould-resistant emulsion paints BAYER AKTIENGESELLSCHAFT (DE) 1997-04-22 — — US disclosed
US-5466693-A FOE USE IN THE CULTIVATION OF RICE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092641-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 TUBB4A 3395/4885TUBB 2746/4885TUBA3C 1125/4885
US-12043600-B2 Microbiocidal compounds MPO, MSR1, PRF1 TUBB4A 1506/4885TUBB 1384/4885TUBA3C 1067/4885
US-11882834-B2 Microbiocidal thiazole derivatives MSR1, TLR1, IFNG TUBB4A 1045/4885TUBB 751/4885TUBA3C 883/4885
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives TLR1, TLR5, IDO1 TUBB4A 988/4885TUBB 909/4885TUBA3C 1671/4885
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide PHF20, FUCA1, ZP1 TUBB4A 2284/4885TUBB 1281/4885TUBA3C 1060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.