SCHEMBL2849656

SCHEMBL2849656

C/C=C(/C(=O)O)n1cccc1C(=O)c1cc(C)cc(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.37
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
ALOX12 P18054 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2107441 1.00 TPMT (0.37) TPMTFNTAFNTBALDH1A1MAPT
SCHEMBL2107437 0.87 TUBB4A (0.33) TPMTFNTAFNTBALDH1A1MAPT
SCHEMBL2107443 0.87 TUBB4A (0.33) TPMTFNTAFNTBALDH1A1MAPT
SCHEMBL27338029 0.83 PPARG (0.35) TPMTALDH1A1MAPTMEN1LMNA
SCHEMBL202896 0.80 TPMT (0.37) TPMTFNTAFNTBALDH1A1MAPT
SCHEMBL202895 0.78 KDM4E (0.31) ALDH1A1MAPTLMNAKDM4EPPARG
SCHEMBL202897 0.77 TPMT (0.34) TPMTFNTAFNTBALDH1A1MAPT
SCHEMBL22074662 0.77 POLB (0.41) FNTAFNTBALDH1A1MAPTLMNA
SCHEMBL29078328 0.77 LMNA (0.32) ALDH1A1MAPTLMNAKDM4E
SCHEMBL13815560 0.73 SMN1; SMN2 (0.40) ALDH1A1MAPTLMNAPOLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043600-B2 Microbiocidal compounds SYNGENTA CROP PROTECTION AG (CH) 2024-07-23 US disclosed
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-06-18 US disclosed
US-11882834-B2 Microbiocidal thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 US disclosed
EP-4271185-A1 DELIVERY SYSTEM FOR PLANT PROTECTION Omya International AG (CH) 2023-11-08 EP disclosed
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide SYNGENTA PARTICIPATIONS AG (CH) 2023-09-05 US disclosed
EP-3717479-B1 MICROBIOCIDAL THIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-07-05 EP disclosed
EP-3941898-B1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-07 EP disclosed
EP-3244732-B1 USE OF SURFACE-REACTED CALCIUM CARBONATE AS CARRIER FOR AGROCHEMICAL COMPOUNDS OMYA INT AG (CH) 2023-05-03 EP disclosed
US-11629129-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 US disclosed
US-11629138-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 US disclosed
US-6893651-B1 Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants BAYER AKTIENGESELLSCHAFT (DE) 2005-05-17 US disclosed
US-6846777-B2 Synergistic biocidal composition THOR GMBH (DE) 2005-01-25 US disclosed
US-20040127520-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2004-07-01 US disclosed
US-6686387-B2 SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2004-02-03 US disclosed
US-20030199490-A1 Synergistic biocidal composition THOR GMBH (DE) 2003-10-23 US disclosed
US-20030092641-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2003-05-15 US disclosed
US-6444667-B1 OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 US disclosed
US-5972971-A WOOD PRESERVATIVE CONSISTS OF A MIXTURE OF METACONAZOLE OR AN ACID ADDITION SALT OR METAL COMPLEX AND IMIDACLOPRID OR SALT OR METAL COMPLEX BAYER AKTIENGESELLSCHAFT (DE) 1999-10-26 US disclosed
US-5622546-A Mould-resistant emulsion paints BAYER AKTIENGESELLSCHAFT (DE) 1997-04-22 US disclosed
US-5466693-A FOE USE IN THE CULTIVATION OF RICE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092641-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 TPMT 2282/4885FNTA 195/4885FNTB 277/4885
US-12043600-B2 Microbiocidal compounds MPO, MSR1, PRF1 TPMT 846/4885FNTA 2900/4885FNTB 1682/4885
US-20040127520-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 TPMT 2282/4885FNTA 195/4885FNTB 277/4885
US-11882834-B2 Microbiocidal thiazole derivatives MSR1, TLR1, IFNG TPMT 262/4885FNTA 3127/4885FNTB 1364/4885
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives TLR1, TLR5, IDO1 TPMT 364/4885FNTA 3555/4885FNTB 3187/4885
US-11629138-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, FPR1 TPMT 1338/4885FNTA 3506/4885FNTB 2785/4885
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide PHF20, FUCA1, ZP1 TPMT 4647/4885FNTA 1315/4885FNTB 2487/4885
US-11629129-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, MSR1 TPMT 849/4885FNTA 3623/4885FNTB 2918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.