Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.52 |
| ▸ | NPC1 | O15118 | 13/20 | 0.52 |
| ▸ | RAB9A | P51151 | 13/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.52 |
| ▸ | GAA | P10253 | 11/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 11/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.52 |
| ▸ | RELA | Q04206 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17123531 | 0.73 | MAPT (0.67) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL11020618 | 0.73 | MAPT (0.67) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL8592761 | 0.72 | MAPT (0.61) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL8592758 | 0.72 | MAPT (0.61) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL21097695 | 0.71 | HSP90AA1 (0.44) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL1231354 | 0.71 | MAPT (0.70) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL1231353 | 0.71 | MAPT (0.70) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL11020602 | 0.70 | MAPT (0.79) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL1165592 | 0.69 | MAPT (0.68) | MAPTNPC1RAB9AKMT2AGAA | |
| SCHEMBL1165591 | 0.69 | MAPT (0.68) | MAPTNPC1RAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11815448-B2 | Method, reagent, and chip for measuring analyte concentration in specimen | TERUMO KABUSHIKI KAISHA (JP) | 2023-11-14 | — | — | US | disclosed |
| US-11739083-B2 | Disposable sensor chip with reagent including 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt | TERUMO KABUSHIKI KAISHA (JP) | 2023-08-29 | — | — | US | disclosed |
| US-20210009578-A1 | DISPOSABLE SENSOR CHIP WITH REAGENT INCLUDING 2-SUBSTITUTED BENZOTHIAZOLYL-3-SUBSTITUTED PHENYL-5-SUBSTITUTED SULFONATED PHENYL-2H-TETRAZOLIUM SALT | TERUMO KABUSHIKI KAISHA (JP) | 2021-01-14 | — | — | US | disclosed |
| US-10851094-B2 | 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt, reagent for biological component concentration measurement containing said salt, and biological component concentration measurement method using said salt | TERUMO KABUSHIKI KAISHA (JP) | 2020-12-01 | — | — | US | disclosed |
| US-20200371020-A1 | METHOD, REAGENT, AND CHIP FOR MEASURING ANALYTE CONCENTRATION IN SPECIMEN | TERUMO KABUSHIKI KAISHA (JP) | 2020-11-26 | — | — | US | disclosed |
| US-20190185465-A1 | 2-SUBSTITUTED BENZOTHIAZOLYL-3-SUBSTITUTED PHENYL-5-SUBSTITUTED SULFONATED PHENYL-2H-TETRAZOLIUM SALT, REAGENT FOR BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT CONTAINING SAID SALT, AND BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT METHOD USING SAID SALT | TERUMO KABUSHIKI KAISHA (JP) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009578-A1 | DISPOSABLE SENSOR CHIP WITH REAGENT INCLUDING 2-SUBSTITUTED BENZOTHIAZOLYL-3-SUBSTITUTED PHENYL-5-SUBSTITUTED SULFONATED PHENYL-2H-TETRAZOLIUM SALT | STUB1, BTK, TST | MAPT 1351/4885NPC1 4612/4885RAB9A 4856/4885 |
| US-20200371020-A1 | METHOD, REAGENT, AND CHIP FOR MEASURING ANALYTE CONCENTRATION IN SPECIMEN | STUB1, MPO, ALDH1A2 | MAPT 3928/4885NPC1 4507/4885RAB9A 4406/4885 |
| US-11815448-B2 | Method, reagent, and chip for measuring analyte concentration in specimen | STUB1, MPO, ALDH1A2 | MAPT 3928/4885NPC1 4507/4885RAB9A 4406/4885 |
| US-10851094-B2 | 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt, reagent for biological component concentration measurement containing said salt, and biological component concentration measurement method using said salt | BPNT1, EPB41, IL4 | MAPT 2736/4885NPC1 2034/4885RAB9A 4392/4885 |
| US-11739083-B2 | Disposable sensor chip with reagent including 2-substituted benzothiazolyl-3-substituted phenyl-5-substituted sulfonated phenyl-2H-tetrazolium salt | STUB1, BTK, TST | MAPT 1351/4885NPC1 4612/4885RAB9A 4856/4885 |
| US-20190185465-A1 | 2-SUBSTITUTED BENZOTHIAZOLYL-3-SUBSTITUTED PHENYL-5-SUBSTITUTED SULFONATED PHENYL-2H-TETRAZOLIUM SALT, REAGENT FOR BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT CONTAINING SAID SALT, AND BIOLOGICAL COMPONENT CONCENTRATION MEASUREMENT METHOD USING SAID SALT | BPNT1, EPB41, IL4 | MAPT 2736/4885NPC1 2034/4885RAB9A 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.