Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 6/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21101917 | 0.73 | KDM4E (0.55) | GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL21102128 | 0.72 | GLS (0.44) | CTSDKMT2APOLB | |
| SCHEMBL20576241 | 0.72 | ALDH1A1 (0.48) | GAAKMT2AALDH1A1 | |
| SCHEMBL15892681 | 0.72 | CTSD (0.61) | CTSDEPHX2GAAKMT2APOLB | |
| SCHEMBL21102124 | 0.71 | RXRA (0.38) | KMT2APOLBKDM4E | |
| SCHEMBL2127169 | 0.70 | GAA (0.62) | GAAALDH1A1 | |
| SCHEMBL21101915 | 0.69 | TACR1 (0.36) | KMT2AKDM4E | |
| SCHEMBL15881389 | 0.69 | MTNR1A (0.50) | CTSDEPHX2GAAKMT2APOLB | |
| SCHEMBL17653947 | 0.69 | ALDH1A1 (0.45) | CTSDEPHX2GAAKMT2AALDH1A1 | |
| SCHEMBL8608649 | 0.68 | L3MBTL1 (0.50) | KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019111225-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF NON‑ALCOHOLIC STEATOHEPATITIS | AVALIV THERAPEUTICS (US) | 2019-06-13 | — | — | WO | disclosed |