SCHEMBL21150772

SCHEMBL21150772

CC(C)(C)OC(=O)CCS(=O)(=O)N1CCC2(CC1)NC(=O)N(c1ccccc1)C2=O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 2/20 0.38
ITGA2B P08514 2/20 0.38
EGLN1 Q9GZT9 2/20 0.38
EGLN3 Q9H6Z9 2/20 0.38
LMNA P02545 1/20 0.37
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36
POLB P06746 2/20 0.36
TACR1 P25103 3/20 0.35
MAPT P10636 1/20 0.35
SLC6A9 P48067 1/20 0.35
GPR119 Q8TDV5 1/20 0.34
USP30 Q70CQ3 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21150773 0.85 ITGB3 (0.47) ITGB3ITGA2BEGLN1EGLN3LMNA
SCHEMBL21151877 0.84 KMT2A (0.48) LMNATACR1NPC1RAB9A
SCHEMBL24974538 0.79 SLC6A9 (0.44) ITGB3ITGA2BLMNASLC6A9
SCHEMBL19534281 0.77 GPR119 (0.51) ITGB3ITGA2BPOLBTACR1GPR119
SCHEMBL24974652 0.75 MT-CO2 (0.42) LMNAPOLBMAPTGPR119NPC1
SCHEMBL21150756 0.74 GPR119 (0.37) LMNAMAPTGPR119NPC1
SCHEMBL21151787 0.73 USP30 (0.54) ITGB3ITGA2BTACR1GPR119USP30
SCHEMBL22256978 0.70 POLB (0.50) ITGB3ITGA2BEGLN1EGLN3LMNA
SCHEMBL23288897 0.70 ITGB3 (0.46) ITGB3ITGA2BPOLBTACR1GPR119
SCHEMBL19534078 0.69 POLB (0.54) ITGB3ITGA2BEGLN1EGLN3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 US disclosed
WO-2019136442-A1 CD16A BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B ITGB3 77/4885ITGA2B 35/4885EGLN1 4635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.