Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675736 | 0.87 | MGAM (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27376723 | 0.87 | MGAM (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL2115321 | 0.87 | LDHA (0.36) | TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL304853 | 0.85 | MGAM (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL28225601 | 0.84 | TDP1 (0.38) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL123402 | 0.82 | TDP1 (0.36) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL29613361 | 0.82 | TDP1 (0.36) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL30773916 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL904451 | 0.81 | — | — | |
| SCHEMBL2475707 | 0.80 | ALDH1A1 (0.38) | TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612394-B2 | Herbicidal malonamides | BASF SE (DE) | 2026-04-28 | — | — | US | disclosed |
| US-20230150989-A1 | HERBICIDAL MALONAMIDES | BASF SE (DE) | 2023-05-18 | — | — | US | disclosed |
| EP-4110763-A1 | HERBICIDAL MALONAMIDES | BASF SE (DE) | 2023-01-04 | — | — | EP | disclosed |
| EP-2627655-B1 | FUSED 3-OXO-PYRAZOLO[4,3-c]PYRIDINE COMPOUNDS AS GABAA MODULATORS | DART NEUROSCIENCE CAYMAN LTD (KY) | 2015-09-16 | — | — | EP | disclosed |
| US-9012470-B2 | Therapeutic 5,6,5-tricyclic analogs | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2015-04-21 | — | — | US | disclosed |
| EP-2627655-A2 | THERAPEUTIC 5,6,5-TRICYCLIC ANALOGS | Dart NeuroScience (Cayman) Ltd (KY) | 2013-08-21 | — | — | EP | disclosed |
| US-20120095016-A1 | THERAPEUTIC 5,6,5-TRICYCLIC ANALOGS | HELICON THERAPEUTICS, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| WO-2012051213-A2 | THERAPEUTIC 5,6,5-TRICYCLIC ANALOGS | HELICON THERAPEUTICS, INC. (US) | 2012-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612394-B2 | Herbicidal malonamides | CBR3, DDT, HACL2 | MGAM 223/4885GAA 1295/4885SI 2840/4885 |
| US-20230150989-A1 | HERBICIDAL MALONAMIDES | DDT, DHRS9, CA9 | MGAM 22/4885GAA 223/4885SI 1461/4885 |
| US-20120095016-A1 | THERAPEUTIC 5,6,5-TRICYCLIC ANALOGS | GABRA5, GABRA6, GABRB1 | MGAM 4785/4885GAA 1516/4885SI 3472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.