Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2959482 | 0.78 | MPO (0.42) | MPOHPGDTSHR | |
| SCHEMBL14612728 | 0.75 | MPO (0.73) | MPOALDH1A1HSD17B10CYP3A4NQO2 | |
| SCHEMBL6552816 | 0.72 | HTR6 (0.53) | HTR6MPOKDM4ERAB9ANPC1 | |
| SCHEMBL27868846 | 0.70 | LMNA (0.39) | HTR6MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL6087130 | 0.69 | CHEK1 (0.33) | MPOMAPTKDM4EALDH1A1LMNA | |
| Butane SCHEMBL14698465 | 0.68 | RAB9A (0.64) | MAPTKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL1612734 | 0.67 | HTR7 (0.41) | MPOHTR7TDP1NQO2MTNR1A | |
| SCHEMBL6086500 | 0.66 | RARA (0.34) | — | |
| SCHEMBL345797 | 0.65 | PRKCI (0.45) | MAPTKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL2975742 | 0.64 | PNMT (0.38) | MPORAB9ANPC1SMN1; SMN2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184556-B1 | METALLOCENE-SUPPORTED CATALYST AND METHOD OF PREPARING POLYOLEFIN USING THE SAME | LG CHEMICAL LTD (KR) | 2019-07-24 | — | — | EP | disclosed |