Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 12/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21219553 | 0.90 | REN (0.42) | TRHRRENCAPN1 | |
| SCHEMBL27639586 | 0.89 | TRHR (0.49) | TRHRRENCAPN1 | |
| SCHEMBL27448784 | 0.89 | TRHR (0.49) | TRHRRENCAPN1 | |
| SCHEMBL27504185 | 0.83 | TRHR (0.59) | TRHRRENCAPN1 | |
| SCHEMBL27518093 | 0.80 | TRHR (0.43) | TRHRRENCAPN1 | |
| SCHEMBL27502009 | 0.80 | REN (0.42) | TRHRRENCAPN1 | |
| SCHEMBL31339185 | 0.77 | EPHX2 (0.51) | TRHRRENCAPN1 | |
| SCHEMBL31339177 | 0.77 | EPHX2 (0.51) | TRHRRENCAPN1 | |
| SCHEMBL29792521 | 0.77 | EPHX2 (0.51) | TRHRRENCAPN1 | |
| Taltirelin SCHEMBL13993039 | 0.77 | TRHR (0.73) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3520795-B1 | COMPOSITION COMPRISING COMBINATION OF TRH ANALOG WITH ARUNDIC ACID, AND PHARMACEUTICALLY ACCEPTABLE SALT OF ARUNDIC ACID | BRIVENTION PHARMACEUTICAL SHANGHAI INC (CN) | 2023-06-14 | — | — | EP | disclosed |
| US-10828303-B2 | Composition comprising combination of TRH analog with arundic acid, and pharmaceutically acceptable salt of arundic acid | Brivention Pharmaceutical (Shanghai) Inc. (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20190240221-A1 | COMPOSITION COMPRISING COMBINATION OF TRH ANALOG WITH ARUNDIC ACID, AND PHARMACEUTICALLY ACCEPTABLE SALT OF ARUNDIC ACID | Brivention Pharmaceutical (Shanghai) Inc. (CN) | 2019-08-08 | — | — | US | disclosed |
| EP-3520795-A1 | COMPOSITION COMPRISING COMBINATION OF TRH ANALOG WITH ARUNDIC ACID, AND PHARMACEUTICALLY ACCEPTABLE SALT OF ARUNDIC ACID | Brivention Pharmaceutical (Shanghai) Inc. (CN) | 2019-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190240221-A1 | COMPOSITION COMPRISING COMBINATION OF TRH ANALOG WITH ARUNDIC ACID, AND PHARMACEUTICALLY ACCEPTABLE SALT OF ARUNDIC ACID | TRHR, TRHDE, CRH | TRHR 1/4885REN 80/4885CAPN1 3820/4885 |
| US-10828303-B2 | Composition comprising combination of TRH analog with arundic acid, and pharmaceutically acceptable salt of arundic acid | TRHR, TRHDE, CRH | TRHR 1/4885REN 80/4885CAPN1 3820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.