Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17591584 | 0.78 | HTR7 (0.50) | LMNAALDH1A1POLBGAAHDAC3 | |
| SCHEMBL13317140 | 0.77 | CES2 (0.52) | LMNACES2CES1L3MBTL1ATM | |
| Water SCHEMBL27746185 | 0.77 | HSD17B3 (0.35) | CES2CES1L3MBTL1HPGDHSD17B3 | |
| SCHEMBL27720896 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1MAPTHPGD | |
| SCHEMBL11775179 | 0.76 | POLB (0.42) | LMNAALDH1A1KDM4EPOLBGAA | |
| SCHEMBL10193619 | 0.75 | ALOX15 (0.50) | LMNAALDH1A1KDM4EPOLBCES2 | |
| SCHEMBL27885970 | 0.75 | HSD17B3 (0.42) | ALDH1A1CES2CES1HTTL3MBTL1 | |
| SCHEMBL27826396 | 0.75 | HDAC3 (0.37) | ALDH1A1HDAC3HDAC1HDAC2HTT | |
| SCHEMBL10193618 | 0.75 | CXCR3 (0.49) | LMNAALDH1A1POLBGAAHTT | |
| SCHEMBL20834527 | 0.75 | LMNA (0.50) | LMNAALDH1A1KDM4ECES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370341-B2 | Compounds and methods of treating infections | NEOCULI PTY LTD (AU) | 2019-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370341-B2 | Compounds and methods of treating infections | ELANE, IL1A, IL1B | LMNA 3006/4885ALDH1A1 1016/4885KDM4E 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.