Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | GCK | P35557 | 2/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241887 | 0.91 | SIRT5 (0.41) | MAPTPOLBMEN1KMT2ACSNK1D | |
| SCHEMBL21242061 | 0.88 | POLB (0.52) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21241931 | 0.88 | MAPT (0.55) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL21241789 | 0.87 | MAPT (0.47) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21241795 | 0.86 | MAPT (0.45) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21241981 | 0.86 | ADORA3 (0.54) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21241854 | 0.86 | MAPT (0.48) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL21241803 | 0.83 | CSNK2A2 (0.41) | MEN1KMT2ACSNK1DPDE5AGCK | |
| SCHEMBL21224260 | 0.83 | MEN1 (0.55) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21241794 | 0.83 | RAB9A (0.44) | MAPTPOLBMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |