Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241931 | 0.84 | MAPT (0.55) | MEN1KMT2ACYP1A2CYP2C9NPC1 | |
| SCHEMBL21241888 | 0.83 | MAPT (0.40) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL21241981 | 0.82 | ADORA3 (0.54) | MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL21241854 | 0.82 | MAPT (0.48) | CSNK2A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL21242061 | 0.82 | POLB (0.52) | MEN1KMT2ALMNANPC1L3MBTL1 | |
| SCHEMBL21224266 | 0.82 | MEN1 (0.54) | MEN1KMT2ALMNANPC1L3MBTL1 | |
| SCHEMBL21241887 | 0.81 | SIRT5 (0.41) | MEN1KMT2ALMNACSNK1D | |
| SCHEMBL21241789 | 0.81 | MAPT (0.47) | CSNK2A2CSNK2BCSNK2A1CSNK2A3GPR139 | |
| SCHEMBL21241795 | 0.81 | MAPT (0.45) | MEN1KMT2ALMNANPC1 | |
| SCHEMBL21242073 | 0.81 | RORC (0.46) | PDE5APDE1APDE1BPDE1CCSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |