Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357015 | 0.85 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| Tetrahydrofuran SCHEMBL27929993 | 0.82 | ALDH1A1 (0.33) | RAPGEF4ALDH1A1MAPT | |
| SCHEMBL1157695 | 0.78 | RAPGEF4 (0.50) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL7911234 | 0.75 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9623685 | 0.75 | RAPGEF4 (0.48) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL13858501 | 0.75 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL13076169 | 0.75 | ACHE (0.39) | RAPGEF4ALDH1A1TSHRCYP1A2CYP2A6 | |
| SCHEMBL23542825 | 0.73 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8966366 | 0.73 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL815941 | 0.73 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102241698-B | Star-shaped triaryl borane compound and preparation method and application thereof | CHINESE ACAD TECH INST PHYSICS | 2013-12-25 | — | — | CN | claimed |
| EP-2906575-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-01-17 | — | — | EP | disclosed |
| US-9831446-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-9831446-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-20170309832-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
| US-9673402-B2 | Platinum metal complexes with divalent groups bridging two ligands | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-20150270500-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150270500-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| EP-2726490-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-20140110642-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| WO-2014056564-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-04-17 | — | — | WO | disclosed |
| US-8241763-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-08-14 | — | — | US | disclosed |
| EP-2038370-B1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20090261717-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
| CN-101473012-A | Material for light-emitting device, and light-emitting device | TORAY INDUSTRIES (JP) | 2009-07-01 | — | — | CN | disclosed |
| EP-2038370-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008006449-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090261717-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, SLC26A3, SLCO4C1 | RAPGEF4 1792/4885ALDH1A1 600/4885KDM4E 2659/4885 |
| US-20150270500-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | RAPGEF4 1864/4885ALDH1A1 3721/4885KDM4E 3816/4885 |
| US-20170309832-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | RAPGEF4 1864/4885ALDH1A1 3721/4885KDM4E 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.