SCHEMBL815941

SCHEMBL815941

Cc1cc(C)c(B(O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 3/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
ORAI1 Q96D31 1/20 0.38
ORAI2 Q96SN7 1/20 0.38
ORAI3 Q9BRQ5 1/20 0.38
TRPV6 Q9H1D0 1/20 0.38
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SELL P14151 1/20 0.35
SELP P16109 1/20 0.35
SELE P16581 1/20 0.35
ACHE P22303 1/20 0.35
CA2 P00918 2/20 0.34
CA1 P00915 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448143 0.82 CA2 (0.43) RAPGEF4ALDH1A1KDM4EGAALMNA
SCHEMBL14436347 0.81 ERN1 (0.36) ERN1
SCHEMBL9945964 0.80 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4EGAALMNA
SCHEMBL16174268 0.79 TDP1 (0.41) RAPGEF4ALDH1A1KDM4EGAALMNA
SCHEMBL1157695 0.75 RAPGEF4 (0.50) RAPGEF4ALDH1A1KDM4EGAALMNA
SCHEMBL24840473 0.74 ACHE (0.46) RAPGEF4ALDH1A1KDM4EGAALMNA
SCHEMBL21642580 0.74 ALDH1A1 (0.33) RAPGEF4ALDH1A1KDM4EGAALMNA
SCHEMBL13858501 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4EGAALMNA
SCHEMBL9623685 0.73 RAPGEF4 (0.48) RAPGEF4ALDH1A1KDM4EGAALMNA
SCHEMBL7911234 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4EGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3662012-B1 HANDLING ADDITIVE FOR SILICONE ELASTOMER BASES DOW SILICONES CORP (US) 2024-08-28 EP claimed
US-11505676-B2 Handling additive for silicone elastomer bases DOW SILICONES CORPORATION (US) 2022-11-22 US claimed
US-20210087360-A1 HANDLING ADDITIVE FOR SILICONE ELASTOMER BASES DOW SILICONES CORPORATION 2021-03-25 US claimed
US-8680306-B2 Complexes and method for synthesis of group 6 organometallics, and use thereof in an olefin metathesis method IFP Energies Nouvelles (FR) 2014-03-25 US claimed
US-8058200-B2 Catalysts for olefin polymerization CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. (US) 2011-11-15 US claimed
US-20110098496-A1 NOVEL COMPLEXES AND METHOD FOR SYNTHESIS OF GROUP 6 ORGANOMETALLICS, AND USE THEREOF IN AN OLEFIN METATHESIS METHOD IFP Energies Nouvelles (FR) 2011-04-28 US claimed
US-20080287721-A1 CATALYSTS FOR OLEFIN POLYMERIZATION CHEVRON PHILLIPS CHEMICAL COMPANY (US) 2008-11-20 US claimed
US-20250388532-A1 ALKYL HALIDE, ALKYLATING AGENT USING SAME, AND METHOD FOR PRODUCING DERIVATIVE OF NUCLEOSIDE TORAY INDUSTRIES, INC. (JP) 2025-12-25 US disclosed
EP-4563570-A1 ALKYL HALIDE, ALKYLATING AGENT USING SAME, AND METHOD FOR PRODUCING DERIVATIVE OF NUCLEOSIDE Toray Industries, Inc. (JP) 2025-06-04 EP disclosed
EP-3662012-B1 HANDLING ADDITIVE FOR SILICONE ELASTOMER BASES DOW SILICONES CORP (US) 2024-08-28 EP disclosed
EP-4405363-A1 NOVEL BORON DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF UNIVERSITE DE BORDEAUX (FR) 2024-07-31 EP disclosed
WO-2023046678-A1 NOVEL BORON DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF Universite de Bordeaux (FR) 2023-03-30 WO disclosed
US-11505676-B2 Handling additive for silicone elastomer bases DOW SILICONES CORPORATION (US) 2022-11-22 US disclosed
EP-0389084-B1 Process for producing a polyborosilazane TONEN CORP (JP) 1995-09-20 EP disclosed
US-5292830-A Silane, silazane, boron block crosslinked copolymers TONEN CORPORATION (JP) 1994-03-08 US disclosed
EP-0519496-A1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same Tonen Corporation (JP) 1992-12-23 EP disclosed
US-5128286-A BORON-CONTAINING, SILICON NITRIDE-BASED CERAMIC SHAPED BODY TONEN CORPORATION (JP) 1992-07-07 US disclosed
US-5030744-A Polyborosilazane and process for producing same TONEN CORPORATION (JP) 1991-07-09 US disclosed
EP-0404503-A1 Boron-containing, silicon nitride-based ceramic shaped body production process Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0389084-A2 Process for producing a polyborosilazane Tonen Corporation (JP) 1990-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098496-A1 NOVEL COMPLEXES AND METHOD FOR SYNTHESIS OF GROUP 6 ORGANOMETALLICS, AND USE THEREOF IN AN OLEFIN METATHESIS METHOD BHMT2, BHMT, TST RAPGEF4 3628/4885ALDH1A1 2006/4885KDM4E 3789/4885
US-20250388532-A1 ALKYL HALIDE, ALKYLATING AGENT USING SAME, AND METHOD FOR PRODUCING DERIVATIVE OF NUCLEOSIDE NSUN2, RNMT, RNGTT RAPGEF4 2625/4885ALDH1A1 3336/4885KDM4E 487/4885
US-20080287721-A1 CATALYSTS FOR OLEFIN POLYMERIZATION POF1B, DBF4, BRPF1 RAPGEF4 79/4885ALDH1A1 1333/4885KDM4E 4584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.