SCHEMBL8966366

SCHEMBL8966366

Cc1cc(C)c(B(Cl)Cl)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 11/20 0.39
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.31
MPI P34949 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30843789 0.82 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL1157695 0.75 RAPGEF4 (0.50) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL7182632 0.74 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL2125698 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL7911234 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL9623685 0.73 RAPGEF4 (0.48) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL13858501 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL28868116 0.72 ALDH1A1 (0.35) ALDH1A1
SCHEMBL23542825 0.71 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4EMAPTLMNA
SCHEMBL357015 0.71 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398317-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-08-26 US disclosed
CN-111326667-B Organometallic compound and organic light-emitting device comprising the same 三星显示有限公司 2025-02-28 CN disclosed
US-11158815-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-26 US disclosed
US-11158815-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-26 US disclosed
US-10971689-B2 Triphenylene-based materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-04-06 US disclosed
WO-2021017274-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MOLECULAR MATERIAL AND SYNTHESIS METHOD THEREFOR, AND ELECTROLUMINESCENT DEVICE 武汉华星光电半导体显示技术有限公司 2021-02-04 WO disclosed
CN-108409766-B Preparation method of boron-nitrogen-containing micromolecules and conjugated macromolecules and application of boron-nitrogen-containing micromolecules and conjugated macromolecules to fluorine ion sensing 西安交通大学 2020-08-18 CN disclosed
US-20200194694-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-18 US disclosed
US-20180269411-A1 TRIPHENYLENE-BASED MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-09-20 US disclosed
US-9985226-B2 Triphenylene-based materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2018-05-29 US disclosed
US-20070082284-A1 Metal complexes with bipodal ligands MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
EP-0519496-B1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same TONEN CORP (JP) 1996-05-22 EP disclosed
EP-0404503-B1 Boron-containing, silicon nitride-based ceramic shaped body production process TONEN CORP (JP) 1996-03-06 EP disclosed
EP-0389084-B1 Process for producing a polyborosilazane TONEN CORP (JP) 1995-09-20 EP disclosed
US-5292830-A Silane, silazane, boron block crosslinked copolymers TONEN CORPORATION (JP) 1994-03-08 US disclosed
EP-0519496-A1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same Tonen Corporation (JP) 1992-12-23 EP disclosed
US-5128286-A BORON-CONTAINING, SILICON NITRIDE-BASED CERAMIC SHAPED BODY TONEN CORPORATION (JP) 1992-07-07 US disclosed
US-5030744-A Polyborosilazane and process for producing same TONEN CORPORATION (JP) 1991-07-09 US disclosed
EP-0404503-A1 Boron-containing, silicon nitride-based ceramic shaped body production process Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0389084-A2 Process for producing a polyborosilazane Tonen Corporation (JP) 1990-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11158815-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 RAPGEF4 3765/4885ALDH1A1 325/4885KDM4E 3511/4885
US-12398317-B2 Organometallic compound and organic light-emitting device including the same ORC3, OCIAD1, PPOX RAPGEF4 4528/4885ALDH1A1 29/4885KDM4E 2236/4885
US-10971689-B2 Triphenylene-based materials for organic electroluminescent devices TERT, PIEZO1, EFNA1 RAPGEF4 2856/4885ALDH1A1 147/4885KDM4E 3934/4885
US-20180269411-A1 TRIPHENYLENE-BASED MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES TERT, PIEZO1, EFNA1 RAPGEF4 2856/4885ALDH1A1 147/4885KDM4E 3934/4885
US-20200194694-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ORC3, OCIAD1, PPOX RAPGEF4 4528/4885ALDH1A1 29/4885KDM4E 2236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.