Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327132 | 0.83 | WNT3A (0.47) | TEKEGLN1MAP4K4MEN1KMT2A | |
| SCHEMBL2320060 | 0.82 | DEGS1 (0.45) | FLT1EGFRIGF1RMETPDGFRB | |
| SCHEMBL212774 | 0.80 | ACHE (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11162903 | 0.80 | CNR2 (0.47) | FLT1EGFRIGF1RMETPDGFRB | |
| SCHEMBL2320830 | 0.79 | CNR2 (0.44) | FLT1EGFRIGF1RMETPDGFRB | |
| SCHEMBL20051805 | 0.78 | USP30 (0.47) | FLT1EGLN1PIM1ALOX5MAP4K4 | |
| SCHEMBL2324964 | 0.78 | EPHB4 (0.48) | KDREPHB4TEKMEN1KMT2A | |
| SCHEMBL5247452 | 0.76 | CNR2 (0.47) | CNR2EGLN1ALOX5MAP4K4TAAR1 | |
| SCHEMBL30679648 | 0.76 | CNR2 (0.47) | CNR2EGLN1ALOX5MAP4K4TAAR1 | |
| SCHEMBL183711 | 0.75 | L3MBTL1 (0.55) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |