Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183711 | 0.85 | L3MBTL1 (0.55) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL212774 | 0.84 | ACHE (0.45) | DEGS1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2320835 | 0.82 | FLT1 (0.44) | EGLN1RAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL2360453 | 0.82 | WNT3A (0.42) | EGLN1RAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL2360146 | 0.82 | TEK (0.49) | KDRTEK | |
| SCHEMBL2321384 | 0.81 | DEGS1 (0.41) | DEGS1EGLN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2325030 | 0.78 | DEGS1 (0.48) | DEGS1EGLN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL2359971 | 0.78 | KIF11 (0.43) | DEGS1RAB9ANPC1KDRTEK | |
| SCHEMBL2324964 | 0.78 | EPHB4 (0.48) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL11472883 | 0.76 | LTA4H (0.47) | DEGS1EGLN1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |