Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362668 | 0.87 | MAPT (0.44) | TDP1GAAHDAC1HDAC6RXRA | |
| SCHEMBL11860220 | 0.78 | LTA4H (0.46) | LTA4HRXRARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL20157547 | 0.76 | MAPT (0.50) | TDP1RXRASMN1; SMN2NPC1MAPT | |
| SCHEMBL20157523 | 0.74 | CES2 (0.39) | ATMGAAHDAC3HDAC1HDAC2 | |
| SCHEMBL20158052 | 0.74 | LMNA (0.39) | TDP1ATMHDAC3HDAC1HDAC2 | |
| SCHEMBL20157317 | 0.74 | NPC1 (0.58) | GAARAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL20157516 | 0.72 | ALDH1A1 (0.48) | TDP1GAARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21351910 | 0.72 | LTC4S (0.38) | TDP1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL603094 | 0.72 | VCP (0.38) | TDP1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3597584 | 0.72 | TP53 (0.54) | ATMLTA4HSMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |