Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157516 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAGAATDP1MAPT | |
| SCHEMBL21362418 | 0.82 | THRA (0.47) | THRBTHRA | |
| SCHEMBL20157552 | 0.81 | LMNA (0.38) | S1PR1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL21362417 | 0.81 | CHRNA7 (0.38) | S1PR1HPGDALDH1A1LMNAGAA | |
| SCHEMBL20157553 | 0.81 | POLB (0.36) | S1PR1HPGDALDH1A1LMNAGAA | |
| SCHEMBL20157560 | 0.80 | PTPN1 (0.43) | S1PR1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL20157757 | 0.78 | LMNA (0.50) | S1PR1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL20157523 | 0.78 | CES2 (0.39) | S1PR1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL21362538 | 0.77 | SRD5A2 (0.39) | S1PR1ALDH1A1LMNAGAATDP1 | |
| SCHEMBL20157557 | 0.77 | PTPN1 (0.39) | S1PR1ALDH1A1LMNAGAAMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |