Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19370719 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBMTNR1AMTNR1BMAOA | |
| SCHEMBL7196687 | 0.68 | SOAT1 (0.39) | MTNR1AMTNR1BACHENPC1RAB9A | |
| SCHEMBL7199649 | 0.67 | PTGS2 (0.41) | MTNR1AMTNR1BMAOAMAOBACHE | |
| SCHEMBL27397679 | 0.66 | TRPA1 (0.42) | MTNR1AMTNR1BMAOAMAOBACHE | |
| SCHEMBL23192186 | 0.65 | SIGMAR1 (0.42) | MTNR1AMTNR1BACHE | |
| SCHEMBL4721993 | 0.64 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBNPC1RAB9ACA12 | |
| SCHEMBL28478574 | 0.63 | MAOA (0.43) | MTNR1AMTNR1BMAOAMAOBACHE | |
| SCHEMBL21694413 | 0.63 | ACHE (0.49) | MTNR1AMTNR1BMAOAMAOBACHE | |
| SCHEMBL15701697 | 0.63 | ACHE (0.42) | SMN1; SMN2MTNR1AMTNR1BMAOAACHE | |
| SCHEMBL7191958 | 0.61 | MAOA (0.41) | SMN1; SMN2MAOAMAOBACHEPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101015-B1 | HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME | EA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |