Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 10/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL28294030 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HTTPTGS2MTNR1AMTNR1B | |
| SCHEMBL7194834 | 0.72 | POLB (0.39) | ALDH1A1MAPTNPSR1HTTNPC1 | |
| SCHEMBL7199649 | 0.72 | PTGS2 (0.41) | PTGS2MTNR1AMTNR1BACHE | |
| SCHEMBL27397679 | 0.72 | TRPA1 (0.42) | PTGS2MTNR1AMTNR1BACHE | |
| SCHEMBL29922720 | 0.70 | HTR1A (0.49) | ALDH1A1PTGS2MTNR1AMTNR1BACHE | |
| SCHEMBL7195698 | 0.70 | HTR1A (0.49) | ALDH1A1PTGS2MTNR1AMTNR1BACHE | |
| SCHEMBL5613920 | 0.69 | HTR2A (0.48) | ALDH1A1PTGS2ACHE | |
| SCHEMBL28478574 | 0.69 | MAOA (0.43) | PTGS2MTNR1AMTNR1BACHE | |
| SCHEMBL21377201 | 0.68 | SMN1; SMN2 (0.34) | PTGS2NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL29922564 | 0.68 | HTR2A (0.47) | ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668865-B1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM NV (NL) | 2003-07-23 | — | — | EP | disclosed |
| US-5990253-A | METALLOCENES HAVING THE INDENE RING BINDING AT THE 2-POSITION RATHER THAN AT THE 1-POSITION; COORDINATION CATALYSTS; LESS CRYSTALLIZATION IN THE ADDITION POLYMERIZATION OF ELASTOMERS | DSM N.V. (NL) | 1999-11-23 | — | — | US | disclosed |
| US-5646322-A | Indenyl compounds and catalyst components for the polymerization of olefins | DSM N.V. (NL) | 1997-07-08 | — | — | US | disclosed |
| EP-0668865-A1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM N.V. (NL) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011406-A1 | INDENYL COMPOUNDS AND CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | DSM N.V. (NL) | 1994-05-26 | — | — | WO | disclosed |