Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390819 | 0.89 | CNR2 (0.32) | JAK1 | |
| SCHEMBL21391098 | 0.88 | JAK1 (0.31) | JAK1 | |
| SCHEMBL21391086 | 0.84 | AR (0.33) | JAK1 | |
| SCHEMBL21354577 | 0.79 | EGFR (0.36) | — | |
| SCHEMBL21390872 | 0.76 | HCAR1 (0.36) | JAK1 | |
| SCHEMBL21390924 | 0.74 | HTR3A (0.34) | JAK1 | |
| SCHEMBL23132031 | 0.74 | CYP11B2 (0.41) | — | |
| SCHEMBL21391096 | 0.74 | JAK1 (0.33) | JAK1 | |
| SCHEMBL21390979 | 0.73 | HDAC1 (0.32) | JAK1 | |
| SCHEMBL21390787 | 0.73 | RORC (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |