Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.33 |
| ▸ | APLNR | P35414 | 3/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 3/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391101 | 0.86 | ALDH1A1 (0.31) | ACSS2SMN1; SMN2 | |
| SCHEMBL21391036 | 0.83 | HDAC1 (0.35) | APLNRACSS2POLBSMN1; SMN2 | |
| SCHEMBL21391169 | 0.81 | BRD4 (0.38) | — | |
| SCHEMBL21391072 | 0.81 | PDE10A (0.34) | ACSS2 | |
| SCHEMBL21390955 | 0.80 | ALDH1A1 (0.32) | ACSS2SMN1; SMN2 | |
| SCHEMBL21390924 | 0.79 | HTR3A (0.34) | APLNR | |
| SCHEMBL21390781 | 0.79 | BRD4 (0.33) | APLNRSMN1; SMN2 | |
| SCHEMBL21391134 | 0.78 | RORC (0.33) | ACSS2SMN1; SMN2RORC | |
| SCHEMBL21390956 | 0.78 | RORC (0.33) | ACSS2SMN1; SMN2RORC | |
| SCHEMBL21390764 | 0.78 | CYP11B1 (0.35) | ACSS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |