Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392335 | 0.83 | MLYCD (0.35) | ALDH1A1KDM4ECACNA1BLMNAPOLB | |
| SCHEMBL21392038 | 0.83 | MAPT (0.35) | KDM4EASPHKDM8LMNAUSP2 | |
| SCHEMBL21392148 | 0.83 | LMNA (0.33) | ALDH1A1PTGER2CACNA1BLMNACXCR3 | |
| SCHEMBL30416683 | 0.81 | CXCR3 (0.35) | ALDH1A1KDM4EPTGER2CXCR3 | |
| SCHEMBL21392147 | 0.81 | CXCR3 (0.35) | ALDH1A1KDM4EPTGER2CXCR3 | |
| SCHEMBL22762439 | 0.80 | LMNA (0.33) | ALDH1A1LMNAL3MBTL1USP2TSHR | |
| SCHEMBL21392320 | 0.78 | USP2 (0.35) | ALDH1A1KDM4EARPTGER2ASPH | |
| SCHEMBL21392246 | 0.76 | APLNR (0.35) | ALDH1A1KDM4EASPHKDM8LMNA | |
| SCHEMBL21392076 | 0.76 | MLYCD (0.33) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL21392159 | 0.73 | SLC2A1 (0.32) | ALDH1A1KDM4ECACNA1BLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179652-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |