Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | APLNR | P35414 | 9/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22762439 | 0.86 | LMNA (0.33) | LMNAMAPTAPLNRALDH1A1SLC2A1 | |
| SCHEMBL21392335 | 0.83 | MLYCD (0.35) | MLYCDLMNAMAPTAPLNRALDH1A1 | |
| SCHEMBL21392148 | 0.83 | LMNA (0.33) | LMNAMAPTAPLNRALDH1A1SLC2A1 | |
| SCHEMBL21392038 | 0.79 | MAPT (0.35) | MLYCDLMNAMAPTKDM4E | |
| SCHEMBL21392292 | 0.76 | ALDH1A1 (0.35) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL21392168 | 0.71 | APLNR (0.33) | LMNAMAPTAPLNRALDH1A1L3MBTL1 | |
| SCHEMBL21392246 | 0.70 | APLNR (0.35) | LMNAAPLNRALDH1A1KDM4EMEN1 | |
| SCHEMBL21391987 | 0.69 | CLK4 (0.36) | LMNAMAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21392075 | 0.68 | ALDH1A1 (0.35) | LMNAMAPTAPLNRALDH1A1L3MBTL1 | |
| SCHEMBL25778776 | 0.67 | CNR2 (0.34) | LMNAMAPTAPLNRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180244-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |