Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 4/20 | 0.33 |
| ▸ | BMP1 | P13497 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392076 | 0.83 | MLYCD (0.33) | MLYCDMEN1KMT2AALDH1A1POLB | |
| SCHEMBL21392292 | 0.83 | ALDH1A1 (0.35) | CACNA1BKMT2AALDH1A1POLBLMNA | |
| SCHEMBL21392078 | 0.82 | MMP9 (0.36) | MLYCDAPLNRBMP1MMP2MMP9 | |
| SCHEMBL30415809 | 0.82 | MMP9 (0.36) | MLYCDAPLNRBMP1MMP2MMP9 | |
| SCHEMBL21392038 | 0.81 | MAPT (0.35) | MLYCDLMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL22762439 | 0.79 | LMNA (0.33) | ALDH1A1APLNRBMP1LMNACYP1A2 | |
| SCHEMBL21392148 | 0.76 | LMNA (0.33) | CACNA1BALDH1A1APLNRLMNACYP1A2 | |
| SCHEMBL21392246 | 0.75 | APLNR (0.35) | MEN1KMT2AALDH1A1APLNRLMNA | |
| SCHEMBL21392070 | 0.71 | MMP9 (0.36) | APLNRBMP1MAPTMMP2MMP9 | |
| SCHEMBL30415869 | 0.71 | MMP9 (0.36) | APLNRBMP1MAPTMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179652-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |