Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.51 |
| ▸ | TUBB | P07437 | 6/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580129 | 0.88 | FOS (0.58) | ALOX15ALOX12CYP1A2CYP3A4TSHR | |
| SCHEMBL31512861 | 0.88 | FOS (0.58) | ALOX15ALOX12CYP1A2CYP3A4TSHR | |
| Alcohol SCHEMBL580127 | 0.84 | FOS (0.54) | ALOX15ALOX12CYP1A2CYP3A4TSHR | |
| SCHEMBL21402293 | 0.83 | TUBB4A (0.55) | ALOX15ALOX12TUBB1TUBB4ATUBB | |
| SCHEMBL8293517 | 0.81 | CYP3A4 (0.65) | ALOX15ALOX12TUBB1TUBB4ATUBB | |
| SCHEMBL21402298 | 0.80 | TUBB4A (0.52) | ALOX15ALOX12TUBB1TUBB4ATUBB | |
| SCHEMBL15259646 | 0.79 | CALM1 (0.50) | TSHRGAA | |
| SCHEMBL21402274 | 0.79 | TUBB4A (0.58) | ALOX15ALOX12TUBB1TUBB4ATUBB | |
| SCHEMBL21402279 | 0.79 | TUBB4A (0.51) | ALOX15ALOX12TUBB1TUBB4ATUBB | |
| SCHEMBL4387213 | 0.78 | ALDH1A1 (0.42) | ALOX15ALOX12TSHRKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569671-B1 | METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2022-06-22 | — | — | EP | claimed |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-05-31 | — | — | US | claimed |
| CN-110168038-B | Methyl menthol derivative and cold sensate composition containing same | 高砂香料工业株式会社 | 2022-05-27 | — | — | CN | claimed |
| US-11236042-B2 | Methylmenthol derivative and cool-sensation imparter composition containing same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-02-01 | — | — | US | claimed |
| EP-3275962-B1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2019-10-02 | — | — | EP | claimed |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-05-31 | — | — | US | disclosed |
| CN-110168038-B | Methyl menthol derivative and cold sensate composition containing same | 高砂香料工业株式会社 | 2022-05-27 | — | — | CN | disclosed |
| US-11236042-B2 | Methylmenthol derivative and cool-sensation imparter composition containing same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | CNR2, ADRB2, TRPA1 | ALOX15 632/4885ALOX12 330/4885TUBB1 755/4885 |
| US-11236042-B2 | Methylmenthol derivative and cool-sensation imparter composition containing same | TRPM8, TRPM4, TRPM2 | ALOX15 2667/4885ALOX12 2711/4885TUBB1 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.