SCHEMBL214416

SCHEMBL214416

Cc1c(S(=O)(=O)c2cc(Br)c(Br)c(Br)c2C)cc(Br)c(Br)c1Br

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 3/20 0.32
LMNA P02545 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ACP1 P24666 2/20 0.31
APEX1 P27695 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38654500 1.00 POLB (0.33) POLBL3MBTL1TSHRLMNAKDM4E
SCHEMBL14854396 0.84 L3MBTL1 (0.35) POLBL3MBTL1TSHRLMNAKDM4E
SCHEMBL6150496 0.78 TDP1 (0.39) APEX1TDP1
SCHEMBL2266180 0.69 CA2 (0.40) TSHRAPEX1TDP1
SCHEMBL9681393 0.67 CYP1A2 (0.41) TSHRALDH1A1APEX1TDP1
SCHEMBL10455151 0.65 LMNA (0.40) POLBL3MBTL1TSHRLMNAALDH1A1
SCHEMBL9682143 0.65 RAPGEF4 (0.47) POLBL3MBTL1TSHRLMNAKDM4E
SCHEMBL11806410 0.65 TDP1 (0.36) APEX1TDP1
SCHEMBL29008152 0.65 TSHR (0.35) TSHRLMNAALDH1A1
SCHEMBL10888797 0.65 THRB (0.40) TSHRLMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1788435-B1 Method of making a lithographic printing plate AGFA GRAPHICS NV (BE) 2013-05-01 EP disclosed
US-8088560-B2 Method of making a lithographic printing plate AGFA GRAPHICS NV (BE) 2012-01-03 US disclosed
EP-1788448-B1 Method for making a lithographic printing plate AGFA GRAPHICS NV (BE) 2009-04-29 EP disclosed
US-20090047603-A1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2009-02-19 US disclosed
WO-2007057413-A1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2007-05-24 WO disclosed
WO-2007057410-A1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2007-05-24 WO disclosed
WO-2007057409-A1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2007-05-24 WO disclosed
EP-1788449-A1 Method for making a lithographic printing plate Agfa Graphics N.V. (BE) 2007-05-23 EP disclosed
EP-1788448-A1 Method for making a lithographic printing plate Agfa Graphics N.V. (BE) 2007-05-23 EP disclosed
EP-1788435-A1 Method of making a lithographic printing plate Agfa Graphics N.V. (BE) 2007-05-23 EP disclosed
EP-0903629-B1 HEAT DEVELOPING PHOTOSENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO LTD (JP) 2003-07-09 EP disclosed
US-6132948-A Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 2000-10-17 US disclosed
US-6132949-A COATING A PHOTOSENSITIVE SOLUTION ON THE SURFACE OF A SUPPORT CONTAINING A PHOTOSENSITIVE SILVER HALIDE, A LATEX BINDER, AN ORGANIC SILVER SALT, A REDUCING AGENT, WATER, TONERS AND AN ORGANIC HALIDE AS AN ANTIFOGGANT SOLID PARTICLES FUJI PHOTO FILM CO., LTD. (JP) 2000-10-17 US disclosed
US-4101323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed