Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.37 |
| ▸ | MYLK | Q15746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974990 | 0.82 | IMPDH2 (0.38) | MAPTIMPDH2CYP19A1GAAKDM4E | |
| SCHEMBL214933 | 0.82 | IMPDH2 (0.38) | MAPTIMPDH2CYP19A1GAAKDM4E | |
| SCHEMBL11511084 | 0.78 | DHFR (0.40) | MAPTALDH1A1MEN1KMT2AIMPDH2 | |
| SCHEMBL16608098 | 0.78 | ALDH1A1 (0.38) | MAPTALDH1A1TDP1CYP19A1GAA | |
| SCHEMBL20354541 | 0.72 | LMNA (0.37) | MAPTPRKCEMYLKALDH1A1TDP1 | |
| SCHEMBL6139697 | 0.72 | FYN (0.35) | ALDH1A1TDP1CYP19A1GAATSHR | |
| SCHEMBL18162711 | 0.72 | ALDH1A1 (0.39) | MAPTPRKCEMYLKALDH1A1TDP1 | |
| SCHEMBL19899827 | 0.71 | MAPT (0.44) | MAPTPRKCEMYLKALDH1A1TDP1 | |
| SCHEMBL108757 | 0.71 | MAPT (0.44) | MAPTPRKCEMYLKALDH1A1TDP1 | |
| SCHEMBL29354986 | 0.71 | MAPT (0.44) | MAPTPRKCEMYLKALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110257361-A1 | ALKYL BENZENE TETRACARBOXYLIC DIANHYDRIDE, MANUFACTURING METHOD THEREOF, POLYIMIDE, AND APPLICATION THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257361-A1 | ALKYL BENZENE TETRACARBOXYLIC DIANHYDRIDE, MANUFACTURING METHOD THEREOF, POLYIMIDE, AND APPLICATION THEREOF | PBRM1, PUF60, ALKBH1 | MAPT 2722/4885PRKCE 3083/4885MYLK 4448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.