SCHEMBL2154641

SCHEMBL2154641

FC(F)(F)c1ccccc1C=S

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.52
GRIN2D O15399 2/20 0.47
GRIN3B O60391 2/20 0.47
GRIN1 Q05586 2/20 0.47
GRIN2A Q12879 2/20 0.47
GRIN2B Q13224 2/20 0.47
GRIN2C Q14957 2/20 0.47
GRIN3A Q8TCU5 2/20 0.47
TNF P01375 2/20 0.46
IL6 P05231 1/20 0.46
MYC P01106 1/20 0.44
MAX P61244 1/20 0.44
MAOB P27338 4/20 0.43
P4HB P07237 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
LMNA P02545 1/20 0.41
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31357193 1.00 NFKB1 (0.52) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2494559 0.80 NFKB1 (0.55) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL323188 0.78 NFKB1 (0.53) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3647881 0.78 NFKB1 (0.53) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL637114 0.78 NFKB1 (0.53) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5286607 0.76 NFKB1 (0.52) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL67207 0.76 NFKB1 (0.57) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5544458 0.76 NFKB1 (0.52) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5544464 0.76 NFKB1 (0.52) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5868149 0.76 ALDH1A1 (0.44) NFKB1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9617207-B2 Method for preparation of perfluoroalkyl sulfenyl chloride Gharda Medical and Advanced Technologies Foundation (IN) 2017-04-11 US claimed
EP-2521712-B1 METHOD FOR PREPARATION OF PERFLUOROMETHYLSULFENYL CHLORIDE GHARDA KEKI HORMUSJI (IN) 2016-12-14 EP claimed
US-20120296119-A1 METHOD FOR PREPARATION OF PERFLUOROALKYL SULFENYL CHLORIDE Gharda Medical and Advanced Technologies Foundation (IN) 2012-11-22 US claimed
EP-2521712-A1 A METHOD FOR PREPARATION OF PERFLUOROALKYL SULFENYL CHLORIDE Gharda, Keki Hormusji (IN) 2012-11-14 EP claimed
WO-2011080752-A1 A METHOD FOR PREPARATION OF PERFLUOROALKYL SULFENYL CHLORIDE GHARDA KEKI HORMUSJI (IN) 2011-07-07 WO claimed
CN-113149873-A Preparation method of trifluoromethyl sulfinyl chloride 浙江埃森化学有限公司 2021-07-23 CN disclosed
US-9984878-B2 Resist under layer film composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-05-29 US disclosed
US-9617207-B2 Method for preparation of perfluoroalkyl sulfenyl chloride Gharda Medical and Advanced Technologies Foundation (IN) 2017-04-11 US disclosed
EP-2521712-B1 METHOD FOR PREPARATION OF PERFLUOROMETHYLSULFENYL CHLORIDE GHARDA KEKI HORMUSJI (IN) 2016-12-14 EP disclosed
US-20160342088-A1 RESIST UNDER LAYER FILM COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-11-24 US disclosed
CN-102791683-B Method for preparing perfluoroalkyl sulfenyl chloride GHARDA KEKI HORMUSJI 2014-12-31 CN disclosed
US-20120296119-A1 METHOD FOR PREPARATION OF PERFLUOROALKYL SULFENYL CHLORIDE Gharda Medical and Advanced Technologies Foundation (IN) 2012-11-22 US disclosed
WO-2001096303-A1 SERINE PROTEASE INHIBITORS ELI LILLY AND COMPANY (US) 2001-12-20 WO disclosed
US-4596880-A Pesticides BAYER AKTIENGESELLSCHAFT (DE) 1986-06-24 US disclosed
EP-0006978-B1 BENZYL ESTERS WITH FLUORINATED ETHER AND/OR THIOETHER GROUPS, THEIR PREPARATIONS AND THEIR USE AS INSECTICIDES; INTERMEDIATE PRODUCTS AND THEIR PREPARATIONS BAYER AG (DE) 1986-01-29 EP disclosed
EP-0041131-B1 PREPARATION OF FLUORO-SUBSTITUTED BENZODIOXOLES AND BENZODIOXANES BAYER AG (DE) 1984-06-13 EP disclosed
US-4438275-A 2,2-DIFLUORO-BENZODIOXOLES BAYER AKTIENGESELLSCHAFT (DE) 1984-03-20 US disclosed
US-4310540-A PYRETHROID-LIKE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1982-01-12 US disclosed
EP-0041131-A2 Preparation of fluoro-substituted benzodioxoles and benzodioxanes BAYER AG (DE) 1981-12-09 EP disclosed
EP-0006978-A2 Benzyl esters with fluorinated ether and/or thioether groups, their preparations and their use as insecticides; intermediate products and their preparations BAYER AG (DE) 1980-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120296119-A1 METHOD FOR PREPARATION OF PERFLUOROALKYL SULFENYL CHLORIDE PFAS, FLI1, PLTP NFKB1 4772/4885GRIN2D 4660/4885GRIN3B 4161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.