Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | IL6 | P05231 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672248 | 0.84 | NFKB1 (0.58) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28924635 | 0.84 | NFKB1 (0.58) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5415307 | 0.82 | NFKB1 (0.39) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2494559 | 0.82 | NFKB1 (0.55) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5410760 | 0.81 | NFKB1 (0.37) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL637114 | 0.80 | NFKB1 (0.53) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3647881 | 0.80 | NFKB1 (0.53) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3721541 | 0.79 | NFKB1 (0.48) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5544464 | 0.78 | NFKB1 (0.52) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5286607 | 0.78 | NFKB1 (0.52) | NFKB1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169674-B1 | ARYL-TRIAZOLYL-PYRIDINES AS PESTICIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-01-20 | — | — | EP | claimed |
| US-10299478-B2 | Pyrazolyltriazolylpyridines as pesticides | BAYER ANIMAL HEALTH GMBH (DE) | 2019-05-28 | — | — | US | claimed |
| EP-3157913-B1 | PYRAZOLYL TRIAZOLYL PYRIDINES AS PESTICIDE | BAYER ANIMAL HEALTH GMBH (DE) | 2019-04-17 | — | — | EP | claimed |
| US-10208015-B2 | Aryl-triazolyl pyridines as pest control agents | BAYER ANIMAL HEALTH GMBH (DE) | 2019-02-19 | — | — | US | claimed |
| WO-2019025153-A1 | USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | claimed |
| US-10065926-B2 | Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-04 | — | — | US | claimed |
| US-20180084782-A1 | METHOD OF CONTROL OF STINKBUGS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-29 | — | — | US | claimed |
| EP-3051946-B1 | USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2017-11-29 | — | — | EP | claimed |
| EP-2953942-B1 | HALOGEN-SUBSTITUTED PYRAZOLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-10-25 | — | — | EP | claimed |
| EP-2964631-B1 | HALOGEN-SUBSTITUTED N-[3-(1H-PYRAZOL-4-YL)PHENYLMETHYL]-SULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES FOR USE IN CROP PROTECTION IN VETERINARY MEDICINE AND IN MATERIAL PROTECTION | BAYER ANIMAL HEALTH GMBH (DE) | 2017-08-30 | — | — | EP | claimed |
| US-20120083463-A1 | Insecticidal and Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2012-04-05 | — | — | US | claimed |
| WO-2012004293-A2 | INSECTICIDE AND FUNGICIDE ACTIVE INGREDIENT COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | claimed |
| US-20110301181-A1 | halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | US | claimed |
| EP-2066628-B1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI AVENTIS (FR) | 2010-10-20 | — | — | EP | claimed |
| EP-2184273-A1 | Halogen substituted compounds as pesticides | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | claimed |
| CN-101495449-A | 2-phenyl-indoles as prostaglandin D2 receptor antagonists | SANOFI AVENTIS (FR) | 2009-07-29 | — | — | CN | claimed |
| US-20090176804-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2009-07-09 | — | — | US | claimed |
| EP-2066628-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Sanofi-Aventis (FR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008014186-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2008-01-31 | — | — | WO | claimed |
| US-6989052-B1 | Phase change ink printing process | XEROX CORPORATION (US) | 2006-01-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10065926-B2 | Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants | SQOR, DHPS, QDPR | NFKB1 2161/4885GRIN2D 1803/4885GRIN3B 3524/4885 |
| US-10299478-B2 | Pyrazolyltriazolylpyridines as pesticides | PRDX4, PRDX1, ATL3 | NFKB1 4388/4885GRIN2D 396/4885GRIN3B 1237/4885 |
| US-20120083463-A1 | Insecticidal and Fungicidal Active Compound Combinations | DDT, ACHE, CYP4B1 | NFKB1 1917/4885GRIN2D 2166/4885GRIN3B 1904/4885 |
| US-20180084782-A1 | METHOD OF CONTROL OF STINKBUGS | BROX, TUBB4B, TUBB4A | NFKB1 694/4885GRIN2D 1493/4885GRIN3B 1407/4885 |
| US-20110301181-A1 | halogen-substituted compounds | L3MBTL4, QSOX1, L3MBTL3 | NFKB1 2430/4885GRIN2D 3334/4885GRIN3B 2939/4885 |
| US-20090176804-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | PTGER2, PTGDR2, CYSLTR2 | NFKB1 1834/4885GRIN2D 465/4885GRIN3B 2231/4885 |
| US-10208015-B2 | Aryl-triazolyl pyridines as pest control agents | PTMS, TYR, PDXK | NFKB1 3800/4885GRIN2D 2029/4885GRIN3B 3262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.