Sugi Predict

Sugi Predict / Compounds / SCHEMBL21550144

SCHEMBL21550144

SCHEMBL21550144

CCS(=O)(=O)c1c(-c2nc3cc(C(F)(F)F)cnc3n2C)nc2ccc(Br)cn12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.41
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ RECQL P46063 1/20 0.37
▸ RXFP1 Q9HBX9 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ TRIM33 Q9UPN9 6/20 0.34
▸ DDR1 Q08345 1/20 0.33
▸ MAOB P27338 1/20 0.32
▸ TRIM24 O15164 4/20 0.32
▸ TRPA1 O75762 2/20 0.32
▸ PIK3CA P42336 1/20 0.31
▸ MTOR P42345 1/20 0.31
▸ NPC1 O15118 2/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ RAB9A P51151 2/20 0.31
▸ PDE5A O76074 1/20 0.31
▸ STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21550152 0.92 POLB (0.43) POLBKDM4ERXFP1TRPA1ALDH1A1
SCHEMBL29658132 0.90 POLB (0.32) POLBMEN1KMT2AKDM4ERECQL
SCHEMBL29358501 0.89 POLB (0.41) POLBKDM4EDDR1TRPA1ALDH1A1
SCHEMBL21805955 0.89 POLB (0.41) POLBKDM4EDDR1TRPA1ALDH1A1
SCHEMBL21550142 0.89 POLB (0.41) POLBTRPA1
SCHEMBL18737470 0.88 POLB (0.40) POLBDDR1MAOBALDH1A1MAPT
SCHEMBL19712048 0.86 POLB (0.40) POLBMEN1KMT2ANPC1ALDH1A1
SCHEMBL19712043 0.85 POLB (0.42) POLB
SCHEMBL19711919 0.85 POLB (0.42) POLBMEN1KMT2ADDR1TRPA1
SCHEMBL21609571 0.84 POLB (0.46) POLBMEN1KMT2AL3MBTL1DDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 — — EP claimed
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-11-06 — — US claimed
WO-2025223904-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-30 — — WO claimed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 — — EP claimed
EP-4618760-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-09-24 — — EP claimed
EP-4618761-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-09-24 — — EP claimed
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-11-28 — — US claimed
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound BASF SE (DE) 2024-11-19 — — US claimed
WO-2024104813-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 — — WO claimed
WO-2024104814-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 — — WO claimed
CN-117998986-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-05-07 — — CN claimed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 — — WO claimed
WO-2019233826-A1 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2019-12-12 — — WO claimed
EP-4739691-A1 SUBSTITUTED PYRIDYL/PYRAZINYL DIHYDROPYRROLOTRIAZINE COMPOUNDS FOR COMBATTING PHYTOPATH-OGENIC FUNGI BASF SE (DE) 2026-05-13 — — EP disclosed
EP-4739690-A1 SUBSTITUTED QUINOLYL/QUINOXALYL DIHYDROPYRROLOTRIAZINE COMPOUNDS FOR COMBATTING PHYTO-PATHOGENIC FUNGI BASF SE (DE) 2026-05-13 — — EP disclosed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 — — EP disclosed
EP-3696177-A1 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2020-08-19 — — EP disclosed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 — — WO disclosed
WO-2019233826-A1 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2019-12-12 — — WO disclosed
WO-2019214979-A1 SUBSTITUTED TRIFLUOROMETHYLOXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2019-11-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, ERG28 POLB 2837/4885MEN1 1734/4885KMT2A 2692/4885
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAT1 POLB 4410/4885MEN1 3142/4885KMT2A 2273/4885
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound ACHE, DDT, MTX2 POLB 2186/4885MEN1 6/4885KMT2A 2876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.