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Sugi Predict / Compounds / SCHEMBL21805955

SCHEMBL21805955

SCHEMBL21805955

CCS(=O)(=O)c1c(-c2nc3cc(C(F)(F)F)cnc3n2C)nc2ccc(Cl)cn12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.41
▸ TRPA1 O75762 2/20 0.37
▸ ALDH1A1 P00352 3/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ CYP2C9 P11712 2/20 0.33
▸ CYP2C19 P33261 2/20 0.33
▸ DDR1 Q08345 3/20 0.33
▸ LMNA P02545 2/20 0.33
▸ GAA P10253 2/20 0.33
▸ XBP1 P17861 1/20 0.33
▸ PPARG P37231 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ NCOA2 Q15596 1/20 0.33
▸ NCOA1 Q15788 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ NCOA3 Q9Y6Q9 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ FADS1 O60427 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358501 1.00 POLB (0.41) POLBTRPA1ALDH1A1CYP1A2CYP2C9
SCHEMBL21550152 0.92 POLB (0.43) POLBTRPA1ALDH1A1KDM4E
SCHEMBL29658126 0.90 FADS1 (0.33) POLBTRPA1ALDH1A1CYP1A2CYP2C9
SCHEMBL21550142 0.89 POLB (0.41) POLBTRPA1
SCHEMBL21550144 0.89 POLB (0.41) POLBTRPA1ALDH1A1DDR1GAA
SCHEMBL29458412 0.88 POLB (0.40) POLBTRPA1ALDH1A1DDR1LMNA
SCHEMBL21805959 0.88 POLB (0.40) POLBTRPA1ALDH1A1DDR1LMNA
SCHEMBL19712043 0.85 POLB (0.42) POLB
SCHEMBL19711919 0.85 POLB (0.42) POLBTRPA1ALDH1A1DDR1PKM
SCHEMBL29658134 0.84 TRPA1 (0.36) POLBTRPA1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 — — EP claimed
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-11-06 — — US claimed
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-11-28 — — US claimed
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound BASF SE (DE) 2024-11-19 — — US claimed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 — — WO claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 — — EP disclosed
US-12564191-B2 Pesticidal compounds BASF SE (DE) 2026-03-03 — — US disclosed
EP-4341258-B1 NEW SUBSTITUTED PYRIDINES AS FUNGICIDES BASF SE (DE) 2025-12-03 — — EP disclosed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 — — EP disclosed
US-20250019361-A1 (3-QUINOLYL)-QUINAZOLINE BASF SE (DE) 2025-01-16 — — US disclosed
EP-4488269-A1 TRIAZOLE COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2025-01-08 — — EP disclosed
EP-4488273-A1 TRIAZOLE COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2025-01-08 — — EP disclosed
WO-2021063735-A1 NEW BICYCLIC PYRIDINE DERIVATIVES BASF SE (DE) 2021-04-08 — — WO disclosed
WO-2021063736-A1 BICYCLIC PYRIDINE DERIVATIVES BASF SE (DE) 2021-04-08 — — WO disclosed
EP-3769623-A1 MESOIONIC IMIDAZOLIUM COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2021-01-27 — — EP disclosed
EP-3766879-A1 PESTICIDAL PYRAZOLE DERIVATIVES BASF SE (DE) 2021-01-20 — — EP disclosed
WO-2020244968-A1 FUNGICIDAL N-(PYRID-3-YL)CARBOXAMIDES BASF SE (DE) 2020-12-10 — — WO disclosed
WO-2020244970-A1 NEW CARBOCYCLIC PYRIDINE CARBOXAMIDES BASF SE (DE) 2020-12-10 — — WO disclosed
EP-3696177-A1 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2020-08-19 — — EP disclosed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, ERG28 POLB 2837/4885TRPA1 2885/4885ALDH1A1 1040/4885
US-12564191-B2 Pesticidal compounds CBR1, CBR3, SCN1B POLB 4047/4885TRPA1 673/4885ALDH1A1 1432/4885
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAT1 POLB 4410/4885TRPA1 1093/4885ALDH1A1 1087/4885
US-20250019361-A1 (3-QUINOLYL)-QUINAZOLINE NQO2, MT-ND4L, MT-ND5 POLB 1645/4885TRPA1 3264/4885ALDH1A1 898/4885
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound ACHE, DDT, MTX2 POLB 2186/4885TRPA1 79/4885ALDH1A1 2413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.