Sugi Predict

Sugi Predict / Compounds / SCHEMBL21635537

SCHEMBL21635537

SCHEMBL21635537

O=[N+]([O-])c1cc(C=NO)c(Cl)cc1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 0.41
▸ KMT2A Q03164 7/20 0.41
▸ L3MBTL1 Q9Y468 3/20 0.41
▸ HSP90AA1 P07900 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ MAPT P10636 6/20 0.40
▸ CRHBP P24387 1/20 0.39
▸ CRHR2 Q13324 1/20 0.39
▸ ESPL1 Q14674 1/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ ATM Q13315 1/20 0.39
▸ ALDH1A1 P00352 6/20 0.38
▸ HPGD P15428 2/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ HTT P42858 3/20 0.37
▸ LMNA P02545 2/20 0.37
▸ VCAM1 P19320 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21635536 1.00 MEN1 (0.41) MEN1KMT2AL3MBTL1HSP90AA1MAPK1
SCHEMBL21635538 1.00 MEN1 (0.41) MEN1KMT2AL3MBTL1HSP90AA1MAPK1
SCHEMBL31580282 1.00 MEN1 (0.41) MEN1KMT2AL3MBTL1HSP90AA1MAPK1
SCHEMBL22714365 0.85 MEN1 (0.49) MEN1KMT2AL3MBTL1HSP90AA1MAPK1
SCHEMBL22714367 0.85 MEN1 (0.49) MEN1KMT2AL3MBTL1HSP90AA1MAPK1
SCHEMBL4647602 0.80 VCAM1 (0.46) MAPK1MAPTESPL1TDP1ATM
SCHEMBL17544061 0.79 TDP1 (0.42) MAPK1MAPTESPL1TDP1ATM
SCHEMBL31580008 0.76 MEN1 (0.34) MEN1KMT2AL3MBTL1HSP90AA1MAPK1
SCHEMBL9756672 0.76 MAPT (0.51) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL9756670 0.76 MAPT (0.51) MEN1KMT2AL3MBTL1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079917-A Substituted isoxazoline carboxylic acid methyl ester compound and preparation method and application thereof — 2026-05-26 — — CN claimed
CN-122079972-A Substituted quinazolinone-isoxazoline compound, and preparation method and application thereof — 2026-05-26 — — CN disclosed
CN-122079917-A Substituted isoxazoline carboxylic acid methyl ester compound and preparation method and application thereof — 2026-05-26 — — CN disclosed
US-12606547-B2 Preparation method of phenylisoxazoline compound SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) 2026-04-21 — — US disclosed
CN-119775214-A Substituted oximido aromatic compound, preparation method thereof, weeding composition and application 青岛金尔农化研制开发有限公司 2025-04-08 — — CN disclosed
US-12202821-B2 Herbicidal compounds SYNGENTA CROP PROTECTION AG (CH) 2025-01-21 — — US disclosed
CN-118084888-A Herbicidal compounds 先正达农作物保护股份公司 2024-05-28 — — CN disclosed
CN-113874368-B Herbicidal compounds 先正达农作物保护股份公司 2024-03-08 — — CN disclosed
CN-113880774-B Preparation method of phenyl isoxazoline compound 沈阳中化农药化工研发有限公司 2023-12-08 — — CN disclosed
EP-3976603-B1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-11-15 — — EP disclosed
EP-3976603-A1 HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-04-06 — — EP disclosed
WO-2022002116-A1 PREPARATION METHOD FOR PHENYLISOXAZOLINE COMPOUND 沈阳中化农药化工研发有限公司 2022-01-06 — — WO disclosed
CN-113880774-A Preparation method of phenyl isoxazoline compound 沈阳中化农药化工研发有限公司 2022-01-04 — — CN disclosed
CN-113874368-A Herbicidal compounds 先正达农作物保护股份公司 2021-12-31 — — CN disclosed
CN-112745305-A Triazinone compound and application thereof 沈阳中化农药化工研发有限公司 2021-05-04 — — CN disclosed
WO-2020239607-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-12-03 — — WO disclosed
CN-105753853-B Isoxazoline-containing uracil compound and application thereof 沈阳中化农药化工研发有限公司 2020-08-04 — — CN disclosed
CN-106536517-B Isoxazoline-containing uracil compound and application thereof 沈阳中化农药化工研发有限公司 2020-03-17 — — CN disclosed
CN-110818699-A Isoxazoline compound and application thereof 沈阳中化农药化工研发有限公司 2020-02-21 — — CN disclosed
US-10550111-B2 Pyrimidine urea compound containing isoxazolines and use thereof SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) 2020-02-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10550111-B2 Pyrimidine urea compound containing isoxazolines and use thereof DDX6, OAT, DHX36 MEN1 4846/4885KMT2A 816/4885L3MBTL1 3456/4885
US-12202821-B2 Herbicidal compounds DDT, ACHE, GSTO1 MEN1 3365/4885KMT2A 1038/4885L3MBTL1 1508/4885
US-12606547-B2 Preparation method of phenylisoxazoline compound CPS1, CBR3, HNMT MEN1 3902/4885KMT2A 806/4885L3MBTL1 2094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.