Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653177 | 0.79 | MAPT (0.46) | CA9NPC1RAB9ACA12MAPT | |
| SCHEMBL21653182 | 0.77 | KMT2A (0.52) | CA9NPC1RAB9ACA12MAPT | |
| SCHEMBL21652915 | 0.77 | CREBBP (0.55) | NPC1RAB9AMAPTTP53CYP1A2 | |
| SCHEMBL21653176 | 0.77 | MEN1 (0.58) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL21652920 | 0.77 | MAPT (0.42) | CA9NPC1RAB9ACA12MAPT | |
| SCHEMBL21653190 | 0.76 | ALDH1A1 (0.54) | NPC1RAB9AMAPTTP53KDM4E | |
| SCHEMBL21653246 | 0.76 | MAPT (0.43) | CA9NPC1RAB9ACA12MAPT | |
| SCHEMBL21653116 | 0.74 | LMNA (0.54) | NPC1RAB9AMAPTCYP2C19ALDH1A1 | |
| SCHEMBL21653054 | 0.74 | HPGD (0.57) | NPC1RAB9AMAPTTP53KDM4E | |
| SCHEMBL21653203 | 0.74 | SMN1; SMN2 (0.46) | CA9RAB9ACA12MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023657-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |