Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2098644 | 0.92 | MAPT (0.51) | ALDH1A1MAPTMAPK1LMNAHTT | |
| SCHEMBL10373626 | 0.83 | MAPT (0.77) | ALDH1A1MAPTMAPK1LMNAHTT | |
| SCHEMBL16404482 | 0.78 | MAPT (0.64) | ALDH1A1MAPTMAPK1LMNAHTT | |
| SCHEMBL1821338 | 0.78 | ALDH1A1 (0.70) | ALDH1A1MAPTMAPK1LMNAHTT | |
| SCHEMBL7513534 | 0.77 | LTA4H (0.47) | ALDH1A1MAPTMAPK1LMNAHTT | |
| SCHEMBL220360 | 0.77 | HTR3E (0.57) | ALDH1A1MAPTLMNAHTTGFER | |
| SCHEMBL662317 | 0.77 | MAPT (0.52) | ALDH1A1MAPTLMNAGFERTDP1 | |
| SCHEMBL3183333 | 0.77 | AKR1C3 (0.44) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL240624 | 0.77 | ADRB1 (0.57) | ALDH1A1MAPTLMNAHTTTDP1 | |
| SCHEMBL1447167 | 0.77 | MLYCD (0.43) | ALDH1A1LMNAGFERMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019736-A | Molecular gel compound designed based on cereblon protein and application thereof | 标新生物医药科技(上海)有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117986271-A | Cell cycle regulator, and pharmaceutical preparation and application thereof | 贵州大学 | 2024-05-07 | — | — | CN | claimed |
| CN-117586233-A | Preparation and application of N- [ (1H-indol-4-yl) alkyl ] benzamide compound | 沈阳药科大学 | 2024-02-23 | — | — | CN | claimed |
| CN-111606883-B | Sulfur-containing compound based on glutarimide skeleton and application thereof | 上海科技大学 | 2023-05-09 | — | — | CN | claimed |
| CN-115611885-A | N-substituted-5- ((4-substituted pyrimidin-2-yl) amino) -1H-indole-2-carboxamide derivatives | 厦门大学 | 2023-01-17 | — | — | CN | claimed |
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-05-12 | — | — | US | claimed |
| EP-3932922-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2022-01-05 | — | — | EP | claimed |
| CN-111606883-A | Sulfur-containing compound based on glutarimide framework and application thereof | 上海科技大学 | 2020-09-01 | — | — | CN | claimed |
| CN-110337293-A | Therapeutic compound | 新泽西鲁特格斯州立大学 | 2019-10-15 | — | — | CN | claimed |
| US-9676789-B2 | Aminated derivative of homoharringtonine, preparation method therefor, and application thereof | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-06-13 | — | — | US | claimed |
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | claimed |
| US-4999355-A | Antiserotonine agents | RHONE-POULENC (FR) | 1991-03-12 | — | — | US | claimed |
| EP-0169581-B1 | ANTITUSSIVE AND MUCUS REGULATING 2-SUBSTITUTED THIAZOLIDINES | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1989-12-06 | — | — | EP | claimed |
| US-4857643-A | Antitussive and mucus regulating 2-substituted thiazolidines | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-08-15 | — | — | US | claimed |
| EP-0266549-A1 | Cinnamyl amines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-05-11 | — | — | EP | claimed |
| EP-0110781-B1 | SUBSTITUTED (AMINO-2-ETHYL)-6-BENZOXAZOLINONES, THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | RIOM LABORATOIRES- C.E.R.M. (Société Anonyme) (FR) | 1987-04-01 | — | — | EP | claimed |
| EP-0169581-A2 | Antitussive and mucus regulating 2-substituted thiazolidines | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1986-01-29 | — | — | EP | claimed |
| US-4556656-A | HYPOTENSIVE, ANTIPSYCHOTIC, DIABETIC, AND ANALGESIC AGENTS | THE UPJOHN COMPANY (US) | 1985-12-03 | — | — | US | claimed |
| US-4521534-A | Imidazo[2,1-a]pyrrolo[2,1-c][1,4]benzodiazepine derivatives, methods of preparation and use | AYERST, MCKENNA & HARRISON, LTD. (CA) | 1985-06-04 | — | — | US | claimed |
| EP-0049203-A1 | Benzoxazolinones substituted in the 6-position by an amino-alcohol or amino-ketone chain, their preparation and their therapeutic use | RIOM LABORATOIRES- C.E.R.M. (Société Anonyme) (FR) | 1982-04-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | GLS, SQOR, GCDH | ALDH1A1 958/4885MAPT 54/4885MAPK1 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.