SCHEMBL2173214

SCHEMBL2173214

CCCCC(=CC1C2CC3CC(C2)CC1C3)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
EPHX2 P34913 5/20 0.38
APEX1 P27695 3/20 0.35
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
HSD11B1 P28845 1/20 0.34
USP2 O75604 1/20 0.34
ALOX5 P09917 2/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
PTGES O14684 1/20 0.31
AKR1B1 P15121 1/20 0.31
GRIK1 P39086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16874413 0.90 L3MBTL1 (0.45) NPSR1L3MBTL1EPHX2HSD11B1USP2
SCHEMBL18259758 0.83 L3MBTL1 (0.40) NPSR1L3MBTL1EPHX2HSD11B1
SCHEMBL3027574 0.83 HSD11B1 (0.38) L3MBTL1EPHX2HSD11B1
SCHEMBL4400851 0.73 HSD11B1 (0.36) HSD11B1
SCHEMBL692340 0.70 GRIK1 (0.51) EPHX2APEX1ALOX5CES2CES1
SCHEMBL322607 0.70 GRIK1 (0.51) EPHX2APEX1ALOX5CES2CES1
SCHEMBL9649905 0.70 HSD11B1 (0.38) L3MBTL1EPHX2ALDH1A1HSD11B1
SCHEMBL244479 0.70 HSD11B1 (0.38) L3MBTL1EPHX2ALDH1A1HSD11B1
SCHEMBL481537 0.68 CES1 (0.48) APEX1ALDH1A1TP53CES2CES1
SCHEMBL88045 0.68 CES1 (0.48) APEX1ALDH1A1TP53CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7972763-B2 Patterns having high resolution; used for semiconductor microfabrication employing a lithography SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-05 US disclosed
US-7862980-B2 Salt suitable for an acid generator and a chemically amplified positive resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-04 US disclosed
US-20080153036-A1 Chemically amplified positive resist compostion SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-26 US disclosed
US-20080081293-A1 Salt suitable for an acid generator and a chemically amplified positive resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-04-03 US disclosed
EP-1558654-A4 NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF FUJIFILM ELECTRONIC MATERIALS (US) 2006-04-05 EP disclosed
EP-1558654-A2 NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF Fujifilm Electronic Materials USA, Inc. (US) 2005-08-03 EP disclosed
US-6916543-B2 Copolymer, photoresist compositions thereof and deep UV bilayer system thereof ARCH SPECIALTY CHEMICALS, INC. (US) 2005-07-12 US disclosed
US-20040137362-A1 Novel copolymer, photoresist compositions thereof and deep UV bilayer system thereof ARCH SPECIALTY CHEMICALS, INC. 2004-07-15 US disclosed
WO-2004040371-A2 NOVEL COPOLYMER AND PHOTORESIST COMPOSITIONS THEREOF ARCH SPECIALTY CHEMICALS, INC. (US) 2004-05-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081293-A1 Salt suitable for an acid generator and a chemically amplified positive resist composition containing the same HCN3, HCN1, NHERF1 NPSR1 806/4885L3MBTL1 3211/4885EPHX2 1108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.