Tetrahydrothiophene

Tetrahydrothiophene

SCHEMBL21833985

C1CCSC1.CC(C)(C)c1cccc2ccccc12.CS(=O)(=O)C(S(=O)(=O)C1CCCCC1)S(=O)(=O)C1CCCCC1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 9/20 0.34
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CNR2 P34972 2/20 0.31
EPHX1 P07099 1/20 0.31
HTR7 P34969 5/20 0.31
EPHX2 P34913 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7541835 0.71 MEN1 (0.40) CNR1MEN1KMT2AEPHX1HTR7
SCHEMBL21833980 0.68 MMP1 (0.36)
SCHEMBL252402 0.66 KIF11 (0.48) TSHR
SCHEMBL29972825 0.66 KIF11 (0.48) TSHR
SCHEMBL4818310 0.66 KIF11 (0.48) TSHR
SCHEMBL3240747 0.66 MEN1 (0.53) CNR1TSHRMEN1KMT2AEPHX2
Cyclobutanol SCHEMBL9815506 0.66 CA2 (0.39) TSHR
SCHEMBL17306777 0.66 RBP4 (0.54) TSHRMEN1KMT2A
Formaldehyde SCHEMBL28441436 0.65 KIF11 (0.44) TSHRMEN1KMT2A
SCHEMBL3779052 0.64 KIF11 (0.47) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200102271-A1 ONIUM SALT, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200102271-A1 ONIUM SALT, RESIST COMPOSITION, AND PATTERN FORMING PROCESS C1R, NHERF1, INSR CNR1 66/4885TSHR 239/4885MEN1 1057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.