Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26097882 | 0.77 | POLB (0.56) | HTR1DPOLBHPGDTSHRRAB9A | |
| SCHEMBL17500086 | 0.73 | CYP2C19 (0.49) | HTR1DPOLBHTR1BCYP2C19CYP1A2 | |
| SCHEMBL19196801 | 0.72 | ALDH1A1 (0.43) | HTR1DHPGDHTR1BCYP2C19CYP1A2 | |
| SCHEMBL21449928 | 0.71 | CYP2D6 (0.41) | HTR1DHPGDTSHRHTR1BCYP2C19 | |
| SCHEMBL20886405 | 0.70 | ALDH1A1 (0.31) | ALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL20000789 | 0.69 | ALDH1A1 (0.40) | HTR1DHPGDHTR1BCYP2C19CYP1A2 | |
| SCHEMBL26802829 | 0.68 | HTR1D (0.45) | HTR1DPOLBHPGDTSHRHTR1B | |
| SCHEMBL17835019 | 0.66 | RAPGEF4 (0.57) | HTR1DPOLBHPGDTSHRRAB9A | |
| SCHEMBL25468639 | 0.64 | POLB (0.40) | HTR1DPOLBHPGDTSHRRAB9A | |
| SCHEMBL9683683 | 0.64 | POLB (0.61) | HTR1DPOLBHPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | HTR1D 400/4885POLB 2574/4885HPGD 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.