Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465657 | 0.91 | HTR6 (0.44) | HTR6PSIP1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL562842 | 0.89 | TDP1 (0.50) | HTR6PSIP1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3456119 | 0.89 | CA2 (0.40) | HTR6PSIP1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1664176 | 0.86 | TDP1 (0.47) | PSIP1TDP1ALDH1A1TSHRMMP1 | |
| SCHEMBL453414 | 0.86 | TDP1 (0.47) | PSIP1TDP1ALDH1A1TSHRMMP1 | |
| SCHEMBL15093651 | 0.84 | RORC (0.37) | HTR6PSIP1TDP1ALDH1A1HSD11B1 | |
| SCHEMBL3454429 | 0.84 | SMN1; SMN2 (0.40) | HTR6PSIP1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6652822 | 0.84 | TDP1 (0.49) | HTR6PSIP1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL218621 | 0.83 | HTR6 (0.44) | HTR6PSIP1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4485970 | 0.81 | PSIP1 (0.52) | HTR6PSIP1TDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | claimed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | SDC2, S100A9, MYH9 | HTR6 3199/4885PSIP1 2899/4885TDP1 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.