Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ME2 | P23368 | 1/20 | 0.35 |
| ▸ | ME1 | P48163 | 1/20 | 0.35 |
| ▸ | ME3 | Q16798 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187044 | 0.81 | TRPC6 (0.40) | ALDH1A1LMNAGAASMN1; SMN2MAPK1 | |
| SCHEMBL2188486 | 0.76 | MAPK1 (0.40) | ALDH1A1LMNAGAASMN1; SMN2ME2 | |
| SCHEMBL2186813 | 0.75 | SCD5 (0.43) | ALDH1A1LMNASMN1; SMN2ALOX15TSHR | |
| SCHEMBL2188684 | 0.74 | KMT2A (0.39) | ALDH1A1LMNAGAASMN1; SMN2ALOX15 | |
| SCHEMBL2186581 | 0.74 | KMT2A (0.52) | ALDH1A1LMNAGAASMN1; SMN2HTT | |
| SCHEMBL2188442 | 0.74 | NPC1 (0.47) | ALDH1A1LMNAGAASMN1; SMN2HTT | |
| SCHEMBL27679675 | 0.74 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2ME2ME1 | |
| SCHEMBL2185718 | 0.73 | LMNA (0.40) | ALDH1A1LMNAGAAPPARGALOX15 | |
| SCHEMBL2187333 | 0.72 | MAPT (0.51) | ALDH1A1LMNASMN1; SMN2HTTALOX15 | |
| SCHEMBL2187029 | 0.71 | L3MBTL1 (0.46) | ALDH1A1LMNAGAASMN1; SMN2ME2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |