Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 9/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187329 | 0.84 | SLC6A4 (0.45) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL5774732 | 0.82 | KDM4E (0.43) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL2188126 | 0.77 | ALDH1A1 (0.50) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL2186733 | 0.75 | KDM4E (0.48) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL2188470 | 0.72 | KDM4E (0.51) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL2186025 | 0.71 | KDM4E (0.46) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL2213735 | 0.71 | KDM4E (0.52) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL2187684 | 0.71 | HSD11B1 (0.48) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL27698607 | 0.70 | KMT2A (0.46) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL27698609 | 0.69 | KMT2A (0.45) | KDM4EBRD4ALDH1A1POLBCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |